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Can two 150 mg doses of Bupropion be taken to reach 300 mg?

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Patient's Query

Hello doctor,

I am currently on Wellbutrin XL 150 mg per I am going to put up to 300 mg before I do so. Our pharmacy is currently out of 300 mg. They do have a generic brand which I do not like. In cases such as this, is it fine to take 2 doses of the 150 mg to make up the 300 mg? Or is that not possible?

Answered by Dr. Suresh Kumar G D

Education:

MBBS

Professional Bio:

Dr. Suresh Kumar G D is a highly skilled specialist in Child Health, Pediatrics, and Psychiatry, with extensive experience in managing developmental, behavioral, and emotional disorders in children and adolescents. His expertise includes early childhood development, ADHD, autism spectrum disorders, and mental health counseling. Dr. Suresh is known for his compassionate, child-centered approach and commitment to promoting holistic well-being in young patients.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

Wellbutrin XL ( Bupropion XL) can be increased to 300 mg XL once daily in the morning after you have been taking Wellbutrin XL for at least four days. The dose has to be increased gradually to minimize the risk of side effects like seizures.

If Wellbutrin XL 300 mg is not available in the pharmacy, you can potentially take two doses of Wellbutrin XL 150 mg, taken together as once daily in the morning (giving you an effective dose of 300 mg once daily). Both pills should be swallowed as a whole and not crushed or chewed. You can switch to Wellbutrin XL 300 mg once it becomes available.

Another easier option will be to try generic Bupropion XL 300 mg tablets as they contain the same active ingredient. I note that you mentioned you do not like it. Is it the medication effect or taste which is not to your liking? If you feel strongly against the generic version, you can take Wellbutrin XL preparation itself.

Whichever option you choose, kindly discuss with your prescribing doctor as some pharmacies will not dispense unless the preparation and dosage are clearly mentioned in the prescription. It is important to have regular follow-ups with your prescribing doctor once the dosage is increased so that benefits and any potential side effects can be monitored.

I hope this helps.

Patient's Query

Thank you doctor,

I have been on 150 mg for eight months now and we have been discussing increasing it to 300 mg. The generic I did try, and it made me very nauseous for some reason. I am not very good at swallowing larger pills. The Wellbutrin is small enough to tolerate. I am hoping 300 mg becomes available so I do not have to take two at once. But if not I guess I will have to until it does.

Answered by Dr. Suresh Kumar G D

Education:

MBBS

Professional Bio:

Dr. Suresh Kumar G D is a highly skilled specialist in Child Health, Pediatrics, and Psychiatry, with extensive experience in managing developmental, behavioral, and emotional disorders in children and adolescents. His expertise includes early childhood development, ADHD, autism spectrum disorders, and mental health counseling. Dr. Suresh is known for his compassionate, child-centered approach and commitment to promoting holistic well-being in young patients.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome back to icliniq.com.

Your clarification makes things clearer. If you are not able to tolerate the generic version, it is better to go with Wellbutrin XL as discussed earlier.

Medically reviewed by iCliniq medical review team
Published At December 10, 2019
Reviewed At May 27, 2024

Education:

MBBS

Professional Bio:

Dr. Suresh Kumar G D is a highly skilled specialist in Child Health, Pediatrics, and Psychiatry, with extensive experience in managing developmental, behavioral, and emotional disorders in children and adolescents. His expertise includes early childhood development, ADHD, autism spectrum disorders, and mental health counseling. Dr. Suresh is known for his compassionate, child-centered approach and commitment to promoting holistic well-being in young patients.

This doctor is not available for online consultations on the platform anymore.

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Bupropion Dose Escalation Helper

Considering a Bupropion Dose Increase?

This quick check helps you understand your options if your doctor has recommended increasing your bupropion dosage. It addresses common concerns like medication availability and tolerability.

Medications should be taken after consulting a physician. The dosages will be prescribed by the physician. Do not alter, start, or stop medications without consulting a healthcare professional. Bupropion can increase the risk of seizures, especially at higher doses, and should not be used if you have a seizure disorder, an eating disorder (such as anorexia or bulimia), or are abruptly stopping alcohol or sedatives; tell your doctor about any of these before a dose increase. If you are having thoughts of harming yourself, seek help immediately (call your local emergency number, or in the US call or text 988). This tool is for guidance only, not a diagnosis.

Education:

MBBS

Professional Bio:

Dr. Suresh Kumar G D is a highly skilled specialist in Child Health, Pediatrics, and Psychiatry, with extensive experience in managing developmental, behavioral, and emotional disorders in children and adolescents. His expertise includes early childhood development, ADHD, autism spectrum disorders, and mental health counseling. Dr. Suresh is known for his compassionate, child-centered approach and commitment to promoting holistic well-being in young patients.

This doctor is not available for online consultations on the platform anymore.

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