HomeAnswersHematologychronic myeloid leukemia

What are the chances of progression of CML with a seven percent blast percentage as per bone marrow biopsy?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

My niece's boyfriend was diagnosed with CML three months back with BCR-ABL positive. He is now stable and is taking Imatinib 400 mg daily. Earlier she was considering engaging with the boy for marriage. Now she wants to know the risk factors she has to face if she goes ahead with the wedding. I have attached the reports. Kindly help.

Answered by Dr. Abdul Aziz Khan

Education:

MBBS

Professional Bio:

Dr. Abdul Aziz Khan is a seasoned Hematologist and Medical Oncologist with extensive expertise in managing blood disorders and cancers. He provides advanced therapies and individualized treatment plans tailored to each patient’s needs. His approach combines clinical excellence with compassionate care, aiming to enhance patient outcomes, improve quality of life, and support individuals throughout their journey with complex hematological and oncological conditions.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

I had gone through the reports attached (attachments removed to protect the patient's identity). CML (chronic myelogenous leukemia) is a chronic disease that is compatible for long survival with current targeted therapy, like tablet Imatinib, but it is difficult to say for how long. It usually transforms into acute leukemia, and the patient dies because of it.

Patient's Query

Hi doctor,

Thank you for the reply.

With existing blasts of 7 % as per bone marrow biopsy, what are the chances of progression of the disease?

Answered by Dr. Abdul Aziz Khan

Education:

MBBS

Professional Bio:

Dr. Abdul Aziz Khan is a seasoned Hematologist and Medical Oncologist with extensive expertise in managing blood disorders and cancers. He provides advanced therapies and individualized treatment plans tailored to each patient’s needs. His approach combines clinical excellence with compassionate care, aiming to enhance patient outcomes, improve quality of life, and support individuals throughout their journey with complex hematological and oncological conditions.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome back to icliniq.com.

For understanding remission, BCR-ABL gene translocation needs to be tested. If positive, Imatinib will be changed to another drug. I suggest reviewing his CBC (complete blood count) with peripheral blood film and BCR-ABL reports.

Medically reviewed by Dr. Sneha Kannan
Published At December 24, 2021
Reviewed At June 25, 2024

Education:

MBBS

Professional Bio:

Dr. Abdul Aziz Khan is a seasoned Hematologist and Medical Oncologist with extensive expertise in managing blood disorders and cancers. He provides advanced therapies and individualized treatment plans tailored to each patient’s needs. His approach combines clinical excellence with compassionate care, aiming to enhance patient outcomes, improve quality of life, and support individuals throughout their journey with complex hematological and oncological conditions.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. Sneha Kannan is a skilled Dental Surgeon with expertise in providing general dental care, including scaling, fillings, and preventive treatments. She does oral surgery procedures such as extractions and minor surgical interventions. She does procedures in restorative dentistry, including crowns, bridges, and dentures. She is an expert in doing endodontic treatments such as root canal therapy. She is well-versed in doing procedures in cosmetic dentistry, including teeth whitening and smile correction. She can provide pediatric dental care for children’s oral health and preventive treatments. She promotes oral hygiene awareness and preventive dental practices.  

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Abdul Aziz Khan is a seasoned Hematologist and Medical Oncologist with extensive expertise in managing blood disorders and cancers. He provides advanced therapies and individualized treatment plans tailored to each patient’s needs. His approach combines clinical excellence with compassionate care, aiming to enhance patient outcomes, improve quality of life, and support individuals throughout their journey with complex hematological and oncological conditions.

This doctor is not available for online consultations on the platform anymore.

Listen to related tracks in our music library
Comprehensive Second Opinion

Read answers about:

imatinibchronic myeloid leukemia

Ask your health query to a doctor online

*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.