HomeAnswersHematologycancerCan mild neutrophilia and borderline high TLC indicate cancer?

Can mild absolute neutrophilia and borderline high TLC be signs of cancer?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

Dr. K. Shobana

Published At November 19, 2021
Reviewed AtFebruary 16, 2023

Patient's Query

Hello doctor,

I have mild absolute neutrophilia and high-end borderline TLC. Can this be a sign of cancer?

Hi,

Welcome to icliniq.com.

I hope you are doing well in the pandemic. The signs and symptoms associated with neutrophilia are those of infections. Sore throat, skin infection, chest infection, and urogenital infections are common. Moreover, neutrophilia can occur due to stress, steroid use, hormone therapy. There is nothing to worry about if there is no fever, malaise, flu. Most people think that a rise in WBC (white blood cells) is related to cancers or leukemia. Please read about leukemia and then make queries, if any.

The word leukemia means white blood cell cancer in the peripheral blood. Leukemia is a relatively old term. Nowadays, it is called hematopoietic and lymphoid neoplasm. A good share of circulating white cells comes from lymphoid tissues such as lymph nodes, spleen, thymus, and the rest of the cells come from bone marrow. Lymphoid tissue is present all over the body, even in the intestine, lungs, liver.

The neoplasms of lymphocyte white blood cells are called lymphomas which are rarely present in the blood. They are present in lymphoid tissue. However, they do infiltrate blood and bone marrow at some later stages (stage 4 disease). Now, certain neoplasms are arising from bone marrow. They are myeloid or lymphoid leukemias. They are most of the time present in peripheral blood.

In addition, leukemia and lymphoma are not merely the presence of certain types of abnormal cells. It is a whole package comprising anemia, leukopenia or leukocytosis, high ESR (erythrocyte sedimentation rate), thrombocytopenia, unexplained fever, weight loss, arthralgias, and myalgias. These are diagnosed using FNAC (fine needle aspiration cytology), bone marrow biopsy, immunohistochemistry, flow cytometry, radiological surveying. These are treated with chemotherapies selected according to the type of cells involved in lesions. Do not forget to send ratings and feedback in the end.

Patient's Query

Thank you doctor,

Thank you for your great explanation. But I want to confirm that mild absolute neutrophilia is not cancer. Is it correct?

Hi,

Welcome back to icliniq.com.

Good to see you again. Yes, you are right. It is not a part of a cancerous process. Stay safe and enjoy life.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Mubashir Razzaq Khan
Dr. Mubashir Razzaq Khan

Hematology

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