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Can Doxycycline cause a burning sensation in the urethra?

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Patient's Query

Hello doctor,

I had unprotected sex with my ex-girlfriend. I became paranoid about catching a sexually transmitted disease like chlamydia as she has had a couple of partners. So I took Doxycycline. After completing the Doxycycline, I started having to burning sensation in my urethra after peeing. I went to a urologist, and he checked my urine for bacteria associated with STDs, but he found nothing. No protein, sugar, or bacteria in my urine. He sent my sample off for deeper analysis, but they still found nothing. I also did a blood test for HIV and syphilis just over a month after exposure, and all came back negative.

Kindly help.

Answered by Dr. Madhav Tiwari

Hello,

Welcome to icliniq.com.

From what you are describing, it seems you may have some urethritis which may be due to unprotected sex. And yes, unnecessary antibiotics are not good for you. But with such a short duration they are not going to cause you any harm. Please help me with a few details:

  1. How old are you?
  2. Are you diabetic or hypertensive?
  3. Have you had any surgeries in the past?
  4. Do you have any other trouble with your urination such as urgency, increased frequency, or feeling of incomplete emptying?
  5. Have you had visible blood in your urine?
  6. Do you have any pain after you ejaculate?
  7. How many times a week do you masturbate or have intercourse?
  8. Are there any new and abnormal-looking lesions on your penis?

Please revert back with the details and I will do my best to assist you.

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Patient's Query

Hello doctor,

Here are the answers to your questions.

  1. I am 49 years old.
  2. I am not diabetic or hypertensive.
  3. I have had no surgeries in the past.
  4. I do not have any unusual urgency to urinate, increased frequency, or feeling of incomplete emptying.
  5. I drink a lot of water every day, so I go quite regularly anyway. Overall, no change in my urination cycle.
  6. I have had no visible blood in my urine. I ejaculated last week then I felt a slight cramp in my testicles because I did not have sex for a while or masturbated, as I was trying to not irritate my urethra, but after ejaculating the burning increased, so that is when I went to the doctor and was prescribed penicillin.
  7. Before this period I masturbated about 3 to 4 times a week, but since this issue, I have not done it like before to not irritate my urethra.
  8. I have have no lesions on my penis. I took a day's break from the medicine.

I have about four more days of the medicine to go. Should I continue taking it?

Answered by Dr. Madhav Tiwari

Hello,

Welcome back to icliniq.com.

To me, it appears that you have developed urethritis (inflammation of the urethral lining) and you may have some prostatitis as well.

Going by your age, there may be a component of an enlarged prostate as well.

Here is what I suggest you to do:

  1. Continue drinking around 3 liters of water per day.
  2. Finish the course of your penicillin as stopping midway is worse than taking it for unindicated reasons.
  3. Visit your urologist and ask for a uroflowmetry test. This will determine how well you are passing urine.
  4. Take over-the-counter anti-inflammatory drugs twice a day for 5 to 7 days.
  5. Ask a urologist to prescribe you an alpha blocker, such as a capsule, of tamsulosin, 0.4 mg at night before bed for a month.
  6. Once the irritation has resolved, continue to masturbate, at least 2 to 3 times a week.
  7. Continue drinking, cranberry juice or lemonade, as that will also help with the burning sensation or irritation.
  8. If you follow the above instructions, I believe you may get significant improvement in a week to 10 days time.

Please let me know if I can help you with anything else, or clarify any other doubts you may have.

I hope this helps.

Answered byDr. Madhav Tiwari

Medically reviewed byiCliniq medical review team

Published At December 28, 2023
Reviewed AtDecember 28, 2023

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Dr. Madhav Tiwari
Dr. Madhav Tiwari

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