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How effective is targeted therapy for my aunt's breast cancer?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

My aunt is affected by breast cancer, and her left breast has been removed. Now, three cycles of chemotherapy are over for her, and she will be getting the fourth chemo next week. Please answer a few of my questions:

  1. What is targeted therapy?
  2. How much is the cost for that, and how much is it effective when compared to normal chemotherapy?
  3. Can targeted therapy help to get cured more quickly than the normal one?
  4. How many cycles should be given to the patients?
  5. Can targeted therapy be given to her now for faster recovery?

Please help.

Hi,

Welcome to icliniq.com.

I understand your concerns.

Targeted therapy is a type of cancer treatment that specifically targets the molecules or pathways involved in the growth and spread of cancer cells. Here are some key points regarding targeted therapy and its application in breast cancer treatment:

1. Mechanism and effectiveness: Targeted therapies work by interfering with specific proteins or receptors on cancer cells that play a role in tumor growth and survival. They are designed to be more selective than traditional chemotherapy, which targets all rapidly dividing cells in the body. This specificity can lead to fewer side effects compared to chemotherapy.

2. Cost: The cost of targeted therapy can vary widely depending on the specific drugs used, the duration of treatment, and the healthcare system in which treatment is received. In many countries, targeted therapies tend to be more expensive than traditional chemotherapy due to their specialized nature and development process.

3. Comparison with chemotherapy: In some cases, targeted therapy can be more effective and have fewer side effects compared to traditional chemotherapy, especially when the cancer cells have specific genetic mutations or characteristics that the targeted therapy can exploit. However, the effectiveness of targeted therapy varies depending on the specific type of cancer and the individual patient's response.

4. Curative potential: Targeted therapy can be highly effective in certain situations and may contribute to a faster recovery compared to chemotherapy alone. However, whether targeted therapy can lead to a cure depends on various factors, including the stage of the cancer, its genetic profile, and how well the patient responds to treatment.

5. Timing and administration: Targeted therapy can be used alongside or following chemotherapy, depending on the treatment plan devised by the oncologist. It is crucial to assess the specific characteristics of breast cancer (such as hormone receptor status, HER2 (human epidermal growth factor receptor 2) status, and genetic mutations) to determine if targeted therapy is appropriate and beneficial.

6. Personalized treatment plan: For your aunt, who has undergone surgery and several cycles of chemotherapy, targeted therapy may indeed be considered as part of her treatment regimen. If her breast cancer is HER2-positive, drugs like Trastuzumab or Pertuzumab could be used as targeted therapies to specifically target HER2-positive cancer cells.

7. Number of cycles: The number of cycles of targeted therapy, like chemotherapy, depends on the specific drugs used, the treatment response, and the overall treatment plan established by the oncologist. Typically, targeted therapies are administered over months to years, depending on the individual patient's response.

Your aunt needs to have a thorough discussion with her treating oncologist regarding the potential benefits and risks of targeted therapy in her specific case. The treating oncologist will consider various factors, including her overall health, cancer characteristics, and previous treatments, to tailor a treatment plan that optimizes her chances for recovery and long-term survival.

I hope this information is helpful to you.

Regards.

Medically reviewed byiCliniq medical review team

Published At August 23, 2024
Reviewed AtSeptember 26, 2025

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