My sister had brain surgery, radiotherapy and now on medication. Kindly interpret her report.

Question

Hello doctor,

My sister had brain surgery this year. After that, she had RT-40, 5GY, and Temodor. Kindly explian her report and present condition.

Answer 1

Hi,

Welcome to icliniq.com.

I hope your sister is doing better after radiation treatment and Temodar.

As we can see, there is an irregular lesion that is likely arising near the selenium of corpus callosum and posterior commissure and extending to the adjacent bilateral peri callosal area across the midline.

The lesion is showing irregular peripheral walls and inferiority the lesion is abutting and bulging in the lateral ventricles.

Features are of concern for a posterior butterfly glioma and glioblastoma multiforme.

Answer 2

Hi,

Welcome back to icliniq.com.

I find a small area of tumor tissue in the periphery of the lesion and the superior part. There is necrosis in the central part of the lesion. However, the walls in some areas show vascularity, and it means that the lesion might have tumor tissue along the walls of the lesion. This is prominent in the lesion's superior midline part, where there is enhancement of the tissues on post-contrast images.

Due respect to your radiologist, spectroscopy is showing necrosis in a larger part of the lesion. Still, we need to take the voxel sample in spectroscopy from an enhancing area in the lesion wall and then see for the spectroscopy pattern. 80 to 90 percent of the lesion is likely showing necrosis, and 10 to 20 percent might be tumor tissue.