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Can Amoxicillin cause rashes in babies?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

My 9-month-old daughter had a rash for three days. It started with small, discreet spots on the legs and lower back. The next day she had a rash on her face and body. These are red, flat spots and it itches. She has no fever and is in good general condition. We consulted a doctor who was thinking about the onset of chickenpox. However, the evolution of the rash does not seem to go in this direction. The doctor cannot give us any other diagnosis. We fear an Amoxicillin rash. The rashes first appeared as small spots, and our daughter finished an 8-day treatment for otitis.

  1. Do you think that is possible?
  2. What else could it be?

Please help.

Thank you.

Answered by Dr. Shanza Ikram

Education:

FCPS

Professional Bio:

Dr. Shanza Ikram is a highly experienced Dermatologist specializing in the diagnosis and treatment of skin, hair, and nail disorders. She is skilled in both medical and cosmetic dermatology, offering advanced treatments for conditions like acne, eczema, pigmentation, and aging concerns. With her patient-focused approach, Dr. Ikram provides personalized care to promote healthy and radiant skin.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

I have gone through your case. In my opinion, there are two to three possibilities for the rash.

  1. First yes, it could be drug eruption as the rash is itchy and appeared after she took treatment for otitis. Drug rash can either occur immediately or even after six weeks.
  2. Second, it could be due to any viral or bacterial infection which first caused otitis and then the rash. But as she did not have a fever and there are no vesicles so in my opinion, it is not chickenpox.
  3. The third possibility is an insect bite or papular urticaria.
  4. The last possibility is Gianotti-Crosti syndrome. It is common in children of this age group and the rash in it is itchy.

Treatment: Please apply 1 percent Hydrocortisone cream on lesions two times a day for ten days. Rash will disappear in two to three weeks.

I hope I have answered your question.

Let me know if I can assist you further.

Thank you.

Patient's Query

Hello doctor,

  1. If it is an Amoxicillin rash, does it mean she has an allergy?
  2. Is there a risk for her to have a more severe reaction (like anaphylactic shock) next time if she takes that drug?

Thank you.

Answered by Dr. Shanza Ikram

Education:

FCPS

Professional Bio:

Dr. Shanza Ikram is a highly experienced Dermatologist specializing in the diagnosis and treatment of skin, hair, and nail disorders. She is skilled in both medical and cosmetic dermatology, offering advanced treatments for conditions like acne, eczema, pigmentation, and aging concerns. With her patient-focused approach, Dr. Ikram provides personalized care to promote healthy and radiant skin.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome back to icliniq.com.

Yes, it means that she is allergic to Penicillin medicine and she should not use it in the future. On the clinical picture, (attachment removed to protect patient identity). I told you three different diagnoses. Confirmation can only be done by skin biopsy. However, clinically it is not chickenpox.

I hope I have answered your question.

Let me know if I can assist you further.

Thank you.

Medically reviewed by Dr. Vinodhini J.
Published At March 17, 2020
Reviewed At January 31, 2025

Education:

FCPS

Professional Bio:

Dr. Shanza Ikram is a highly experienced Dermatologist specializing in the diagnosis and treatment of skin, hair, and nail disorders. She is skilled in both medical and cosmetic dermatology, offering advanced treatments for conditions like acne, eczema, pigmentation, and aging concerns. With her patient-focused approach, Dr. Ikram provides personalized care to promote healthy and radiant skin.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. Vinodhini J. is a Dental Surgeon with extensive years of clinical experience. She specializes in the diagnosis, prevention, and treatment of dental and oral health issues, including restorative, surgical, and cosmetic procedures. With a patient-centered approach, she focuses on maintaining oral health, alleviating discomfort, and enhancing smiles. Her expertise ensures comprehensive care tailored to each patient’s dental needs and overall wellbeing.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

FCPS

Professional Bio:

Dr. Shanza Ikram is a highly experienced Dermatologist specializing in the diagnosis and treatment of skin, hair, and nail disorders. She is skilled in both medical and cosmetic dermatology, offering advanced treatments for conditions like acne, eczema, pigmentation, and aging concerns. With her patient-focused approach, Dr. Ikram provides personalized care to promote healthy and radiant skin.

This doctor is not available for online consultations on the platform anymore.

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