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How are autism spectrum disorders linked to the brain?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have been reading about autism spectrum disorders and how they relate to the brain. Can you explain how neuroimaging helps in understanding these disorders on a deeper level? Also, I have heard something about proteins being involved. Could you shed some light on that connection and its significance in the context of autism? Kindly guide.

Thank you.

Hello,

Welcome to iclinq.com.

I can understand your concern.

Your interest in the scientific underpinnings of ASD (Autism spectrum disorders) is commendable. By leveraging neuroimaging and proteomic research, we are gaining deeper insights into these multifaceted neurodevelopmental conditions.

  • Advanced tools like MRI (magnetic resonance imaging) and fMRI (Functional magnetic resonance imaging) provide detailed visualizations of brain structure and function in individuals with ASDs.
  • Atypical brain activity patterns are observed during tasks related to language, social interaction, and sensory perception.
  • Genetic research has identified hundreds of genes potentially linked to ASDs, many of which code for proteins involved in critical brain functions.
  • Proteins essential for building and maintaining synaptic connections (synapses) are implicated in some ASD cases, impacting neuronal communication.
  • Dysfunctions in proteins involved in neuronal signaling are also being investigated as potential contributors to ASDs.

I hope this information will help you.

Thank you.

Medically reviewed byiCliniq medical review team

Published At April 12, 2024
Reviewed AtJuly 18, 2024

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