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Is Tezspire more effective than other biologics for asthma?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

My 14-year-old son has severe, uncontrolled asthma that is becoming life-threatening despite aggressive treatment. He currently uses Symbicort and Montelukast but still requires emergency room visits almost monthly, with two ICU admissions this year. His pulmonologist has recommended starting Tezspire injections, as his previous biologic (Fasenra) did not significantly improve his symptoms. His asthma seems to be triggered by nearly everything, like minor colds, exercise, changes in the weather, and even stress from school. He has missed so much school that he is now at risk of repeating the grade, and he is becoming increasingly anxious and depressed about his condition. We have already eliminated all possible triggers from our home, including rehoming our beloved family dog. Is Tezspire significantly more effective than other biologics for severe asthma in adolescents? What are the potential long-term side effects for someone his age?

We are desperate for anything that might prevent another terrifying episode of respiratory distress.

Please help.

Thank you.

Answered by Dr. Kaushal Bhavsar

Education:

MBBS

Professional Bio:

Dr. Kaushal Bhavsar is an Internal Medicine specialist and Pulmonologist. He completed his MBBS at M. P. Shah Medical College, Jamnagar, Gujarat and MD at PDU Medical College, Rajkot. He has 15 years of clinical experience and is currently working at GMERS Medical College and Sola Civil Hospital, Gujarat.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I understand your concern.

Tezspire (Tezepelumab) will not work wonders because he has already taken one biologic drug, which is not beneficial. So better to avoid it.

I hope this helps.

Kindly follow up if you have more concerns.

Thank you.

Medically reviewed by iCliniq medical review team
Published At June 9, 2025
Reviewed At September 9, 2025

Education:

MBBS

Professional Bio:

Dr. Kaushal Bhavsar is an Internal Medicine specialist and Pulmonologist. He completed his MBBS at M. P. Shah Medical College, Jamnagar, Gujarat and MD at PDU Medical College, Rajkot. He has 15 years of clinical experience and is currently working at GMERS Medical College and Sola Civil Hospital, Gujarat.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Kaushal Bhavsar is an Internal Medicine specialist and Pulmonologist. He completed his MBBS at M. P. Shah Medical College, Jamnagar, Gujarat and MD at PDU Medical College, Rajkot. He has 15 years of clinical experience and is currently working at GMERS Medical College and Sola Civil Hospital, Gujarat.

This doctor is not available for online consultations on the platform anymore.

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