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Can I take antihistamines (an OTC drug) when pregnant?

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Patient's Query

Hello doctor,

Can I take antihistamines (an OTC drug) when pregnant?

Answered by Dr. Gowrimeena

Hi,

Welcome to icliniq.com.

Antihistamines are used to treat allergy symptoms. We have two generations of antihistamines:

First generation antihistamines like Chlorpheniramine, Dimenhydrinate, Diphenhydramine, Doxylamine are considered safe to use during pregnancy. These medications have a sedative effect (cause sleepiness).

The newer non-sedating antihistamines like Cetirizine, Desloratadine, Fexofenadine, and Loratadine are best avoided in pregnancy as we have no strong evidence confirming its safety in pregnancy.

Hope this helps.

Consult a general medicine physician online for further queries.

Answered byDr. Gowrimeena

Medically reviewed byiCliniq medical review team

Published At October 16, 2014
Reviewed AtMay 6, 2025

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Gowrimeena
Dr. Gowrimeena

Obstetrics and Gynecology

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