Can you please see my liver function test results and tell me how serious this is?

Hello,

Welcome to icliniq.com.

Well, the seriousness of this depends upon what is causing this nearly double rise in ALT (Alanine transaminase) and AST (Aspartate transaminase) levels. But generally speaking, they are not that much worse. The values above five times the normal are usually severe. Your weight seems to be in control, so fatty liver disease does not seem to cause it. Alcohol intake, viral infections, certain drugs like Paracetamol and antibiotics, herbal supplements, anabolic steroids, and finally some metabolic diseases such as Wilson's disease (copper accumulation in the liver) and hemochromatosis (iron accumulation in the liver) are the causes. The treatment of it also depends upon what we are dealing with.

• Can you tell me your age? And for how long have you noticed this change in the liver function tests?
• Do you intake alcohol?
• Do you have any viral infections, namely hepatitis B or hepatitis C, or have you been exposed to one of these?
• Do you have any family history of liver disease, viral or otherwise, or any addictive drug use, like Cannabis, NMDA (N-Methyl-D-aspartic acid), or recent use of Paracetamol?
• Do you have any fever, yellowish eyes, dark-colored urine, or itching?

Kindly provide the above information to understand your case better, and we can guide you optimally for the correction of these abnormal liver function tests.

Hi,

Welcome back to icliniq.com.

Thanks for providing this essential information. I think this is alcohol, which is causing this problem. A man should be taking no more than 21 standard drinks in a week. If I am not wrong, units mean a number of standard drinks? Cutting it down is the best strategy. However, if you have been drinking for quite a long time, say more than ten years, and with the same amount you mention, I suggest you have some additional testing to make sure everything is alright.

It includes,

• Ultrasound abdomen.
• Fibroscan (transient elastography) of the liver.
• Serum albumin.
• Rule out hepatitis B and hepatitis C infection by doing HbsAg (hepatitis B virus surface antigen), HB core total, and anti HCV (hepatitis C) antibody.

For now, you have moderate the alcohol intake and repeat liver function tests in four weeks.