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Can diabetes cause mesenteric vascular thrombosis, septic shock, and ARF?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I have diabetes mellitus with a myeloproliferative disorder, massive upper gastrointestinal bleeding, mesenteric vascular thrombosis, and septic shock with ARF. How do I get this?

Hi,

Welcome to icliniq.com.

The main cause of your problem is diabetes mellitus. Diabetes is a prothrombotic condition, creating a clot that blocks the mesenteric veins draining the intestine. Blockage of these vital veins causes decreased blood flow to the intestines, causing ischemia and infarction of the intestine. This results in poor renal perfusion, and finally, ARF (acute renal failure) occurs due to it. In other words, increased pressure in the portal veins causes portal hypertension. It causes upper gastrointestinal bleeding. There is decreased renal perfusion, which increases the pressure in the Bowman's capsule of nephrons in the kidney, causing damage to the kidney. So, it results in ARF (acute renal failure).

I hope this helps.

Thank you.

Answered byDr. Pratap V G M

Medically reviewed byDr. Sneha Kannan

Published At September 2, 2020
Reviewed AtDecember 12, 2025

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