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Use of Surgical Mesh in Pelvic Organ Prolapse

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A surgical mesh is a medical device that provides additional support to repair weak or damaged tissue. The use of this is discussed in the article.

Medically reviewed byDr. Richa Agarwal

Published At October 27, 2023
Reviewed AtDecember 7, 2023

Introduction:

Pelvic organ prolapse means the pelvic muscles cannot adequately support the organs in the pelvic area. The organs slip down from their normal position, which creates a bulge in the vagina (a tube that extends from the external genitals to the cervix). The use of surgical mesh in such cases is a standard procedure. The benefits of using this surgical mesh to treat pelvic organ prolapse outweigh the risks.

What Is a Surgical Mesh?

The surgical mesh is a flat panel-like screen to strengthen the tissue or bone. This is composed of synthetic polymers or biological polymers.

The various materials used for synthetic mesh are:

  • Synthetic non-absorbable polymers, like polypropylene.

  • Synthetic absorbable polymers, like polyglycolic acid.

  • Biological (cellular collagen that is sourced from cows or pigs).

  • Composite means a combination of any of the above materials.

Most surgical meshes are made up of non-absorbable materials.

What Are the Signs of Pelvic Organ Prolapse?

  • A feeling of pressure or fullness in the pelvic area.

  • Severe backache in the lower region.

  • A sense of something dropping from the vagina.

  • The extreme urge to urinate frequently.

  • Urination problems such as leakage of urine.

  • Severe constipation.

  • The loss of control of the bowel.

  • Slight spotting from the vagina.

  • In some cases, severe bleeding from the vagina.

In What Procedure Is Surgical Mesh Used?

  • The surgical mesh is used in pelvic organ prolapse cases and stress urinary incontinence (SUI). Stress urinary incontinence means leakage of urine during physical activity, which elevates abdominal pressure, and those activities are coughing, sneezing, laughing, or exercising.

  • In pelvic organ prolapse cases, the pelvic organs shift downward and bulge out of the vagina. The pelvic floor muscles are too weak to hold the organs in position. The pelvic organs undergo prolapse: the urinary bladder, uterus (womb), rectum, and vagina. The causative factors for pelvic organ prolapse are pregnancy, delivery, and aging. The bladder is prolapsed in most cases.

  • In stress urinary incontinence, the weak pelvic muscles and tissues cause the bladder and neck to move downward.

How Is the Surgical Mesh Placed in the Treatment of Pelvic Organ Prolapse?

  • Surgical mesh is placed permanently to strengthen the vaginal wall in pelvic prolapse cases and support the urethra in stress in urinary incontinence cases.

  • Transvaginal (through the vagina) mesh insertion to treat pelvic organ prolapse.

  • Transabdominal mesh insertion to treat pelvic organ prolapse.

  • Pelvic organ prolapse management can also be done without using a surgical mesh. In such cases, the incisions are usually made in the vagina and closed with sutures. The surgeries in which surgical mesh is used are more successful than those without surgical mesh.

What Are the Merits and Demerits of Considering Surgery for Pelvic Organ Prolapse?

  • Before proceeding with any treatment, consider other treatment options, including non-surgical and suture-based methods that do not use mesh. They are very effective in the long run and without complications that occur with surgical mesh.

  • Perform the surgery with or without the use of surgical mesh. Using mesh may increase the risk of complications involving mesh and subsequent surgeries. In some cases, additional surgeries cannot solve all the medical issues. Proper medical consultation with the physician is essential to determine the best treatment.

What Are the Complications of Using Surgical Mesh in Pelvic Organ Prolapse Cases?

  • Vaginal mesh erosion is the most common complication that occurs after using the surgical mesh to strengthen the pelvic organ prolapse and stress urinary incontinence. Using non-absorbable surgical synthetic mesh, which is made of polypropylene or polyester, can wear away or break in the long run. The part of the mesh can remain and may become exposed or protrude through the vagina. This is vaginal mesh erosion.

  • Erosion of mesh to other organs as the mesh, over time, can protrude into other organs like the urethra, urinary bladder, or rectum.

  • The vaginal mesh contraction means the surgical mesh shortening or tightening in the long run. This leads to the shortening of the vagina and severe pain. The vagina can also contract over time.

  • There is severe pain during sexual intercourse.

  • Urinary bladder and urination problems.

  • Risk of infections.

  • Profuse bleeding.

  • The pelvic organ prolapse can re-occur.

  • Urinary tract injury.

  • Trauma to the ureter.

  • Rectal injuries.

  • Neuro-muscular problems.

  • Fistula (an uncommon passage or connection between two body parts such as an organ, blood vessel, and other structures).

  • Perforation of internal organs.

  • Severe discharge from the vagina.

The Surgical Mesh-Related Complications Are:

  • Mesh Extrusions: This is a severe complication of the surgical mesh placement. The vaginal mucosa erosions due to surgical mesh protrusion were detected on examination of the vagina between two to twenty-four weeks after surgery. All women with mesh extrusions experience severe pain. The treatment is the application of vaginal cream and removal of a part of the exposed mesh. In extreme cases, surgical removal of the mesh is recommended.

  • Transvaginal Mesh: The surgical mesh is placed through the vagina to treat pelvic organ prolapse. The risks are more than the benefits, so the Food and Drug Administration (FDA) banned the use of transvaginal mesh.

  • Infection: Infection associated with mesh usage. Necrotizing fasciitis means chronic bacterial infection that destroys the tissue under the skin caused by Streptococci.

  • Mesh Shrinkage: The shrinkage of the surgical mesh causes severe complications. They are severe vaginal pain, dyspareunia (painful intercourse), shortening of the vagina, obstruction of the urethra, and occurrence of pelvic organ prolapse. The treatment is surgical mesh removal by mobilizing the mesh, dividing the fixation arms of the mesh, and excisioning the shrunk mesh. The shrinkage leads to visceral injury and severe bleeding.

  • Specialized professionals must place the surgical mesh in pelvic organ prolapse.

  • The patient should be well informed about the mesh placement complications beforehand. The potential postoperative complications of a mesh surgery compared to a non-mesh surgery and their effect in the long run.

  • Watch for complications and be vigilant toward the patient.

  • Follow-up consultations are needed in such cases.

Conclusion:

The surgical mesh placement in pelvic organ prolapse is under review, and a thorough knowledge of the mesh-associated complications is necessary before planning treatment. The mesh placement is invasive, and the insertion must be done with utmost care. Modern surgical methods for treating pelvic organ prolapse are minimally invasive with no severe complications.

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Frequently Asked Questions

Various factors play a pivotal role in the onset of pelvic organ prolapse. Among them, vaginal childbirth emerges as a significant contributor, especially in cases of traumatic or multiple deliveries. The persistence of chronic constipation also underscores its relevance. Additionally, as women age, the weakening of pelvic muscles becomes increasingly evident, exacerbated by factors such as obesity, which imposes undue pressure. Persistent coughing further compounds the risk, alongside regular heavy lifting activities.

Treatment avenues for pelvic organ prolapse encompass both non-surgical and surgical approaches. Non-surgical interventions encompass the utilization of a pessary, a removable device designed to support the prolapsed muscles. Additionally, pelvic floor exercises, such as Kegel exercises, prove instrumental in fortifying pelvic musculature. Dietary modifications, including increased fiber intake, facilitate smoother bowel movements, alleviating symptoms. In cases of severe pain and discomfort, surgical intervention becomes imperative. Surgical management entails the repair of weakened pelvic floor muscles.

Surgical mesh, a crucial tool in medical intervention, comprises a flat panel-like screen primarily crafted from synthetic materials, predominantly synthetic polypropylene. Alternatively, it can be fashioned from biological materials. Its primary purpose is reinforcing weakened or damaged tissues within the pelvic muscles or organs. By providing supplementary support, this mesh aids in restoring the affected tissues to their rightful position. It facilitates the resumption of normal functionality, contributing to the patient's overall recovery and well-being.

In addition to the utilization of surgical mesh, alternative methods are available for addressing pelvic organ prolapse. These encompass the use of pessaries, removable devices strategically placed within the vagina to offer support to the pelvic organs, alongside kegel exercises aimed at strengthening the pelvic floor muscles. Surgical interventions offer further options, such as reattaching drooping pelvic organs to either the pelvic floor muscles or the bone through sutures facilitated by laparoscopy. Another surgical approach is laparoscopic sacropexy, wherein the weakened structure is affixed to the sacrum using polypropylene tape.

The deployment of surgical mesh, while offering benefits, is not without its associated risks. These encompass a spectrum of complications, ranging from vaginal mesh erosion and contraction to discomfort during sexual intercourse. Furthermore, there are risks of infections, urinary complications, and potentially severe outcomes like profuse bleeding or urinary tract injuries. In rare instances, rectal injuries or the formation of fistulas, abnormal connections between bodily structures, may occur. Additionally, there is a risk of perforation of internal organs and the presence of abnormal discharge from the vagina.

Recent studies have highlighted the efficacy of surgical mesh in numerous cases of pelvic organ prolapse (POP) repair. However, due to the array of associated complications, the effectiveness and safety of this approach have become the focal points of intense debate and controversy. Notably, in the UK (United Kingdom), the National Institute for Health and Care Excellence (NICE) has banned transvaginal mesh due to serious safety concerns, reflecting the ongoing scrutiny and caution surrounding its usage.

The recovery trajectory after pelvic organ prolapse repair involving mesh hinges upon the specific surgical approach undertaken. Following open surgery, the healing process typically lasts four to six weeks. Conversely, in laparoscopic surgery, the healing period is notably shorter, typically ranging from one to two weeks.

Long-term complications linked with surgical mesh in pelvic organ prolapse encompass erosion of the mesh, potentially inducing discomfort and pain. Infections may ensue, necessitating antibiotic treatment, while urinary complications such as retention or tract infections can occur. Pain during sexual intercourse and nerve damage due to the mesh further contribute to the spectrum of potential issues.

Suppose a patient exhibits symptoms such as discomfort, protrusion, pain, pressure, activity limitations, bladder issues, urinary incontinence (involuntary urine leakage), tampon difficulties, or painful intercourse. In that case, they might qualify as a candidate for pelvic organ prolapse (POP) surgery involving mesh. However, certain risk factors can heighten the likelihood of complications associated with mesh. Hence, thorough assessment and consideration of these factors are imperative before surgery.

While surgical mesh is a treatment option for certain types of pelvic organ prolapse and urinary incontinence, it is crucial to recognize that it may not be suitable for every case. Despite its application in addressing these conditions, surgical mesh utilization is fraught with numerous complications. Recognizing these concerns, the FDA (Food and Drug Administration) has issued warnings regarding its usage, advocating for patients and healthcare providers to explore alternative treatment avenues.

When considering alternatives to surgical mesh for mending pelvic organ prolapse, options abound. Native tissue repair stands out as a method for the restoration of the patient's tissues. Alternatively, biological grafts serve as supportive structures for the prolapsed organ. Other avenues include the insertion of pessaries within the vagina, engaging in pelvic floor exercises, and implementing lifestyle adjustments such as avoiding heavy lifting. Each approach offers distinct benefits and considerations for patients seeking alternatives to surgical mesh.

Indeed, the potential for pelvic organ prolapse (POP) recurrence post-surgery involving mesh exists. Contributing factors to its recurrence include mesh-related complications like erosion or infection, the specific surgical technique employed, and the inherent strength of the patient's pelvic tissues. Furthermore, post-surgery activities, such as heavy lifting or straining during bowel movements, can exacerbate the likelihood of recurrence. Understanding these factors is essential for patients and healthcare providers in managing and mitigating the risk of POP recurrence.

While the typical duration of pelvic organ prolapse surgery utilizing mesh is approximately one hour, several variables can sway this timeframe. Factors such as the intricacy of the selected technique, the patient's overall health condition, and the surgeon's experience all play pivotal roles in determining the duration of POP surgery.

Implementing lifestyle modifications is paramount to managing pelvic organ prolapse. These adjustments include refraining from heavy lifting for six to eight weeks, steering clear of vigorous exercise, and avoiding straining during bowel movements. Additionally, discontinuing smoking habits, incorporating pelvic floor exercises into one's routine, maintaining a healthy weight, and scheduling regular follow-ups with healthcare providers are integral to comprehensive management.

Following pelvic organ prolapse surgery involving mesh, the initial follow-up appointment typically occurs around six months after the operation. Subsequent follow-up appointments are then scheduled at three-month intervals, followed by six-month intervals, and eventually transition to annual appointments. Long-term follow-up appointments may be arranged annually to monitor for any signs of symptom recurrence or complications diligently.

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