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Aluminum Nitrate Toxicity - Associated Health Problems and Prevention

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Aluminum nitrate is a chemical substance used for different applications. Read the article below on how to handle the chemical and prevent toxicity.

Written by

Dr. Pallavi. C

Medically reviewed by

Dr. Kaushal Bhavsar

Published At May 17, 2023
Reviewed AtOctober 26, 2023

What Is Aluminum Nitrate?

Aluminum is associated with a chemical compound known as aluminum nitrate. Its uses include: tan leather, make antiperspirants, prevent corrosion, extract uranium, refine petroleum, and act as a nitrating agent. The most prevalent metal in the earth's crust is aluminum, which is always combined with other elements, including oxygen, silicon, and fluorine. Methemoglobinemia is a hazardous condition caused by nitrite.

What Are the Health Problems That Occur Due to Aluminum Nitrate?

Acute Health Problems:

1. Swallowing: Accidental substance intake may be deadly; animal investigations show that less than 150 grams can be lethal or seriously affect a person's health. The drug and its metabolites may bind to hemoglobin and prevent the body from absorbing oxygen normally. This "methemoglobinemia" syndrome is oxygen deprivation (anoxia). Breathing issues and cyanosis, (bluish staining of the skin and mucous membranes) are symptoms.

The onset of symptoms may take many hours following exposure.

  • 15 % Exposure: The lips, nose, and earlobes exhibit cyanosis at a blood methemoglobin content of around. Although euphoria, flushed cheeks, and headaches are often reported symptoms, they may not always exist.

  • 25 to 40 % Exposure: There is noticeable cyanosis, but there is little additional impairment than the output of physical effort.

  • 40 to 60 % Exposure: Symptoms include fatigue, weakness, dizziness, lightheadedness, headaches that get progressively worse, ataxia (affecting coordination and balance), fast, shallow breathing, sleepiness, nausea, vomiting, disorientation, lethargy, and stupor.

  • Over 60 % Exposure: Dyspnea (shortness of breath), respiratory depression, tachycardia or bradycardia (changes in heart rhythm), and convulsions are symptoms when the percentage.

  • Above 70 % Exposure: It can be lethal.

2. Eye: Evidence suggests that some people may have eye discomfort and ocular impairment 24 hours after installing certain materials. With discomfort, severe inflammation may be anticipated. The cornea may sustain injury. Without quick and sufficient therapy, visual loss may be irreversible. Constant exposure can lead to conjunctivitis (inflammation of the conjuctiva of the eye).

3. Skin: The substance may cause the skin to become mildly but significantly inflamed, either immediately upon direct touch or after a brief interval. Contact dermatitis (allergic inflammation of the skin), characterized by redness, swelling, and blistering, can be brought on by repeated exposure. One should not expose this material to skin that is inflamed, abraded, or open to the air. Entry into the bloodstream, such as through wounds, abrasions, or lesions, may result in systemic damage with negative consequences.

4. Inhaled: Some evidence supports the claim that the substance can irritate certain people's respiratory systems. The body's reaction to such irritability may result in further lung damage. If high levels of particulate matter are breathed, those with reduced respiratory function, airway disorders, and illnesses like emphysema or chronic bronchitis (inflammation of the airways) may become even more disabled.

Chronic Health Problems:

  • Experimental findings imply that this substance may impair embryo or baby development without maternal poisoning symptoms.

  • There is some evidence that consistent or prolonged occupational exposure may have a cumulative impact on the health of organs or biochemical systems.

  • Particles smaller than 0.5 microns can penetrate the lung and stay there for an extended period, resulting in pneumoconiosis, which can alter lung function.

  • Breathlessness is the main symptom, and an X-ray will show lung shadows. Alzheimer's disease is a degenerative brain condition linked to heavy aluminum exposure.

What Are the Safety Precautions to Be Taken to Avoid the Exposure?

  • Wear chemical protection gloves, such as PVC (polyvinyl chloride).

  • Put on rubber or other protective shoes or boots.

  • Use determines whether a glove type is suitable and durable.

  • The gloves can be chosen based on significant aspects such as the frequency and length of contact, the glove material's chemical resistance, the glove's thickness, and the gloves' dexterity.

  • Use gloves that have undergone relevant testing.

  • Only wear gloves with clean hands. Hands should be completely cleansed and dried after wearing gloves. It is advised to use a moisturizer without fragrance.

  • Avoid wearing cotton or cotton-backed gloves.

  • Avoid using leather gloves.

  • Protect an individual's eyes with chemical safety glasses.

  • Ensure full-face protection.

  • Special risks are associated with contact lenses; both soft and hard lenses can concentrate irritants.

  • If exposure is significant, a PVC protection suit could be needed.

  • Ensure that a safety shower is easily accessible.

  • Some plastic personal protection equipment (PPE) is not advised because it may generate static electricity, such as gloves, aprons, and overshoes.

What First Aid Can Be Done In Case of Accidental Exposure?

Swallowed:

  • Immediately seek medical attention if swallowed.

  • If medical assistance is not immediately accessible, and the patient is more than 15 minutes away from a hospital, contact a doctor or a poison control center for advice if otherwise directed.

  • Emergency hospital care will likely be required.

  • If the patient is awake, offer water to drink and induce or trigger vomiting by running the fingers down the back of the throat. To keep the airway open, tilt the patient forward or put them on their left side (head down if feasible).

  • Care should be taken to wear gloves while inducing vomiting in the patients.

Eyes:

  • Accidental exposure to the eyes should be addressed immediately by rinsing with clean, flowing water.

  • By keeping the eyelids apart and away from the eye and sometimes elevating the top and lower lids, one may ensure thorough irrigation of the eye.

  • Seek medical assistance if the pain is severe or keeps happening.

Skin:

  • Remove all contaminated clothing and footwear. Use water to wash the skin and hair (and soap if available). In case of inflammation, seek medical care.

Accidental Inhalation:

  • If vapors or combustible products are inhaled, the patient should be shifted to a safe location.

  • Seek medical help immediately.

How to Handle and Store the Aluminium Nitrate?

Follow the manufacturer's instructions for handling and storage.

  • Avoid coming into contact with or breathing in any dust, mist, or fumes.

  • Do not forget to ventilate properly.

  • Wear safety gear at all times, and wash off any spills from clothes.

  • Keep the material away from heat, light, combustibles, and flammables.

  • Be careful not to damage the containers.

  • Never repack or transfer unwanted components back to their original containers.

  • Only take out the amount that is needed.

  • Decomposition brought on by contamination might result in flames and extremely high temperatures.

  • Never eat, drink, or smoke while handling aluminum nitrate.

  • After handling, always wash the hands with soap and water.

  • Never repack. Use only the containers the manufacturer provides.

  • For materials with low viscosity, drums and jerricans can be used.

  • A can must have a screwed enclosure to be used as inner packaging.

  • Removable head packaging and cans with friction closures may be utilized for substances and solids with higher viscosity.

  • If inner glass packages are utilized in combination packages, there must be enough inert cushioning material in touch with the inner and outside packages. Additionally, there must be enough inert absorbent to catch any spills in inner glass packaging containing liquids.

Conclusion

Aluminum nitrate is a toxic substance that needs to be handled carefully. Proper care and expert advice are necessary to prevent accidental exposures. Always take necessary safety measures and keep medical assistance within 15 minutes of reach. In addition, employees should be provided with proper training in handling chemical substances and delivering first aid.

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Dr. Kaushal Bhavsar
Dr. Kaushal Bhavsar

Pulmonology (Asthma Doctors)

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