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Systemic Diseases of the Foot - Understanding Symptoms and Treatment

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Several systemic disorders can manifest in the feet and impact foot health. Read this article to learn more.

Written byDr. Sameeha M S

Medically reviewed byDr. Kaushal Bhavsar

Published At May 16, 2024
Reviewed AtJuly 25, 2024

Introduction

Various systemic disorders or conditions affect the entire body and develop as symptoms in the feet. Gout, diabetes mellitus, neurological problems, and arthritis are examples of systemic diseases that impact the overall health of the foot and a person's capacity to walk comfortably. Seeking advice from a podiatrist as soon as possible is crucial if someone suspects a systemic illness. When dealing with systemic foot diseases, it is critical to inspect the affected areas regularly to identify any further issues early.

What Are the Systemic Conditions That Impact the Foot?

Neurological disorders, gout, diabetes mellitus, and arthritis are common systemic conditions that impact a patient's ability to walk easily and affect general foot health.

1. Gout:

The typical signs of gout include pain, swelling, and redness around the base of the big toe at the metatarsal or phalangeal joint. Gout occurs when there is an abnormal level of uric acid accumulation in the body. Excess uric acid crystallizes and accumulates in ligaments, tendons, joints, and the surrounding bone and muscle tissue. This condition is frequently treated with non-steroidal anti-inflammatory drugs to ease pain and inflammation, as well as other medications to reduce levels of uric acid in the body. Gout is most common in those who are overweight, follow low-protein diets, and live sedentary lifestyles.

2. Diabetes Mellitus:

An increase in blood sugar that the body cannot control with bodily insulin is known as diabetes mellitus. The three kinds of diabetes are type I, type II, and gestational diabetes (pregnancy-related). All these conditions signal that the body is not creating enough insulin or using the insulin it generates adequately. Gestational diabetes exclusively affects pregnant women who have never had symptoms of the condition before.

Diabetes is often associated with two major foot concerns. They include peripheral vascular disease and diabetic neuropathy. Diabetic neuropathy (nerve damage in diabetic patients) can cause nerve degeneration and numbness in the feet, resulting in a loss of sensation. Peripheral vascular disease reduces blood supply to the foot and, in severe cases, necessitates amputation. Diabetes can create peripheral disorders that affect the foot, such as athlete's foot, fingernail and toenail infections, corns (thickened skin), blisters (fluid-filled spaces in the skin), bunions (bony bumps), severe dry skin, plantar warts (rough bumps), and ingrown toenails. All of these can be attributable to decreased blood supply to the foot.

3. Neurological Disorders:

Foot control may be directly or indirectly impacted by anomalies in the nervous system that influence the innervation of the lower limbs. Several circumstances, including underlying neurological conditions, can cause foot and ankle disorders. These include injury to the peripheral nerves, cerebral palsy (a congenital disorder affecting muscle tone), Charcot-Marie-Tooth disease (a progressive nerve condition), and particular abnormalities of the toes such as claw toe (a bend in the toe that resembles a claw), mallet toe (a toe deformity), and hammertoe (a toe deformity).

4. Rheumatoid Arthritis (RA):

Foot health can be severely impacted by rheumatoid arthritis. The foot's bones and joint structures may be damaged by rheumatoid arthritis, making walking extremely painful. The extent of the inflammation may be such that it impairs the appearance and functionality of the joints and other body parts. The joints of the hand may become malformed as a result. This makes it challenging to move the fingers. It is uncertain what causes explicitly rheumatoid arthritis. When someone has RA, their body's immune system attacks healthy tissues and cells. As a result, inflammation develops inside and around the joints. This could be damaging to the skeletal system. Heredity is one of the potential contributing factors, according to scientists. RA can occur to anyone at any age. However, it often impacts those between the ages of 30 and 50. It affects women more often than it does males.

5. Systemic Lupus Erythematosus:

SLE is most affected by skin and joints, a chronic autoimmune condition affecting many organs and tissues. SLE can occasionally result in foot discomfort, inflammation, and other symptoms like rashes, tiredness, and stiff joints. Systemic lupus erythematosus-related foot disorders can affect any of the tissue structures of the foot or ankle. Some examples are joint discomfort and swelling, skin lesions that cause extra pain, tenderness, and vascular or neurological symptoms in the lower limbs.

What Are the Complications Associated With Diabetes-Related Foot Conditions?

Any skin, nerve, or circulation problems with the foot are more likely to become infections or other complications if someone has diabetes. Foot and toe conditions that could lead to complications include cuts, ulcers, burns, blisters that do not heal, dry or cracked skin, corns, and calluses. Gangrene and Charcot's foot are significant complications of diabetes-related foot issues.

  • Untreated foot infections can lead to gangrene (a severe condition where blood flow to a part of the body stops), causing tissue death. Gangrene is a medical emergency and can be fatal without immediate treatment.

  • Charcot foot is a rare complication of diabetes-related neuropathy. If not properly treated, it can cause the joints in the foot to collapse and lead to permanent disability. These changes can also increase the risk of severe or spreading infections in the foot.

How Are Systemic Foot Diseases Managed?

A modern multidisciplinary strategy is necessary for treating individuals with severe systemic conditions. A comprehensive evaluation is crucial in these situations where the patient has co-morbidities and additional musculoskeletal conditions. The patient's care depends heavily on the team's ability to communicate effectively with the other medical specialists. Physicians, podiatrists, orthopedists, vascular surgeons, occupational therapists, and physiotherapists constitute them.

Treatment of the primary systemic condition is critical for managing its impact on the feet. This could involve taking treatments like insulin therapy for diabetes, urate-lowering medications for gout, or medicines for rheumatoid arthritis. One must practice proper foot care to avoid complications and preserve the health of the feet.

This involves cleaning and moisturizing the feet regularly to avoid dryness and cracking and checking them every day for wounds, sores, or indications of infection. Lifestyle modifications can aid in managing systemic foot disorders and lessen their damage to foot health. This can include keeping a healthy weight, eating a balanced diet low in purines and carbohydrates (for gout and diabetes, respectively), and stopping cigarette smoking.

What Are the Practical Tips to Improve Circulation for People With Diabetes?

Poor circulation in people with diabetes can reduce blood supply to the feet, making cuts and sores slow to heal. Signs of circulation issues may include leg pain or cramps while walking. Causes of circulation problems include artery hardening or narrowing due to smoking, high blood fats, and elevated blood glucose levels.

Tips to improve circulation for people with diabetes:

  • Manage blood fat levels.

  • Maintain normal blood glucose levels.

  • Quit smoking to prevent blood vessel spasms and narrowing.

  • Exercise daily with brisk walking to promote blood flow throughout the body.

Conclusion

All systemic conditions affecting the foot can be effectively treated to decrease muscle and joint damage if detected early and managed with appropriate medication and lifestyle changes. To keep the glucose levels in their blood as close to normal as possible, individuals with diabetes must check them regularly and speak with their doctors frequently. Patients with rheumatoid arthritis should check with their doctor to verify they take the proper medications to limit joint damage.

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