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Influence of Hormonal Imbalances on Dementia

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Correcting hormonal imbalances can significantly improve dementia. Read the article to know more.

Medically reviewed by

Dr. Abhishek Juneja

Published At June 30, 2023
Reviewed AtJuly 4, 2023

Introduction

In today’s world, dementia is prevalent in younger and older individuals due to food and lifestyle habits. Dementia may cause loss of consciousness, contributing to poor cognitive and decision-making abilities. In 2020, the World Health Organisation estimated that about 50 million people were living with dementia, which may triple in 2050. Hormones play a crucial role in influencing dementia and may aggravate the condition. Advanced age is the most common risk factor in influencing dementia. Though there are various causes, like smoking, high blood pressure, and diabetes, identifying the exact cause may help with prompt treatment. Correcting the hormonal imbalance with hormonal replacement therapy could be helpful in a few cases, but it may not completely cure dementia. This article explains in detail the significant role of correcting hormonal imbalance and their effects on dementia.

What Is Dementia?

The loss of memory, thinking, and problem-solving abilities that interfere with the daily life of an individual is called dementia. The most common form of dementia is Alzheimer’s disease. Due to the progressive nature of the condition, there is no cure for this condition. However, certain medical interventions can help cope with the symptoms and aid the slow progression of the disease. In addition, it is important to provide a supportive environment for such individuals, along with physical exercise and social engagement can improve the overall well-being of the individual.

What Are the Types of Dementia?

Dementia is of several types; each is distinct and has its own characteristics. The most common types of dementia are listed below:

  • Vascular Dementia - It occurs due to disruption in the blood supply to the brain, leading to brain cell damage. It occurs after a stroke and is characterized by problems in judgments and planning.

  • Lewy Body Dementia - Lewy bodies are a type of abnormal proteins that accumulate in the brain. They cause a decline in cognitive abilities, along with hallucinations, alertness, and fluctuations.

  • Frontotemporal Dementia - It is characterized by the degradation of the frontal and temporal lobes of the brain. It changes the personality, language, and behavior. It quite often results in social and emotional disinhibition.

  • Parkinson's Disease - It is a neurodegenerative disorder that causes dementia. Individuals with this condition may experience difficulty in movement along with cognitive decline and problems with memory.

  • Vascular Dementia - The blood supply to the brain is disrupted, leading to damage in the blood vessels. It manifests as a stroke and is characterized by difficulty in planning and attention.

What Causes Dementia?

Any damage to the nerve cells (neurons) and their brain connections may cause dementia. Depending on the area of damage, the symptoms exhibited by each individual may vary widely. In dementia, it is common to find deposits of protein in the brain. As the condition progresses, some individuals may find it difficult to struggle with basic tasks such as eating and dressing. This significantly impairs the person’s quality of life and the ability to function on their own.

What Are the Symptoms of Dementia?

The symptoms of dementia may vary depending on the cause, some of which are listed below:

  • Cognitive changes like memory loss, difficulty in communicating, confusion, disorientation, and challenges in communication. In addition, difficulty in driving and handling complex tasks are some of the symptoms.

  • Psychological changes like anxiety, depression, hallucinations, and inappropriate behavior are commonly seen.

What Is the Hormonal Imbalance?

The abnormality in the levels or functioning of hormones in the body is called hormonal imbalance. Hormones are chemical messengers and are involved in various body processes like growth, metabolism, and reproduction of overall health. These hormones are secreted by various glands like the thyroid, pituitary, and adrenal glands. It affects both men and women at different stages of life. It may result in a wide range of symptoms and health issues.

What Causes the Hormonal Imbalance?

The causes of hormonal imbalance are listed below:

  • With age, a natural fluctuation in hormonal imbalance is prone to occur.

  • Stress can cause a major imbalance in hormone levels.

  • Endocrine disorders like hypothyroidism and hyperthyroidism. And diabetes contributes to hormonal imbalance.

  • Lifestyle factors like poor nutrition, lack of exercise, excessive alcohol, and inadequate sleep can contribute to hormonal imbalance.

Can Correcting Hormonal Imbalances Prevent Dementia?

Both hormonal imbalance and dementia are separate medical conditions. Studies are yet to prove that correcting hormone levels can significantly improve dementia. Hormonal imbalance takes an overall toll on the health and lifestyle of an individual. Dementia is due to the accumulation of abnormal brain proteins and is a degenerative process. However, hormones play an important role in the risk or progression of the disease.

For example, the predominant hormone in women, estrogen, has a relation to dementia risk. A few studies show that hormonal replacement therapy in postmenopausal women is associated with a reduced risk of dementia. Likewise, thyroid hormone imbalance in conditions like hypothyroidism and hyperthyroidism has cognitive effects. Hypothyroidism has an impact on the cognitive abilities of an individual by causing memory impairment and confusion.

Hormonal imbalances may not directly prevent dementia; however, managing overall health can contribute to the well-being of an individual and support brain health. Also, a healthy lifestyle, regular exercise, and a balanced diet are beneficial for overall brain health and may reduce the risk of cognitive decline. In addition, stress management plays a crucial role in today’s lifestyle. Prioritizing the risk factors contributing to cardiovascular health, managing blood pressure and diabetes is essential. Managing these risk factors can help to improve the symptoms of dementia.

Conclusion

Therefore, correcting hormonal imbalances may not completely cure dementia; however, it can keep the disease under control and prevent progression. It is important to take care of an individual's overall health by following a balanced diet, engaging in physical activities, and getting adequate rest. Also, preventing dementia may require a multi-faceted approach that includes various factors like lifestyle, medical conditions, and genetic predisposition. Early diagnosis of the condition and prompt treatment can help manage the symptoms and lead a quality life.

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Dr. Abhishek Juneja
Dr. Abhishek Juneja

Neurology

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