HomeHealth articlesolder adultsWhat Are the Signs and Symptoms of Catatonia in Older Adults?

Catatonia in Older Adults - A Detailed Review

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Catatonia (lack of neurotransmitters) affects the elderly and is a neuropsychiatric syndrome characterized by a range of motor abnormalities and altered mental states.

Written by

Swetha. R.

Medically reviewed by

Dr. Abhishek Juneja

Published At December 18, 2023
Reviewed AtDecember 18, 2023

Introduction

Catatonia is a condition that has long been recognized in the field of psychiatry, but its prevalence and impact on older adults have received limited attention. Older adults are more able to affect both medical and psychiatric conditions, and catatonia can be one of them. Understanding catatonia in this demographic is crucial for timely diagnosis and effective management.

What Is Catatonia in Older Adults?

Catatonia (neuropsychiatric condition) is a set of motor and behavioral symptoms. In older adults, catatonia may manifest as a state of immobility or excessive motor activity. Typically, over 65 people are affected by catatonia, experiencing a range of unusual behaviors and movements. These can include staying very still, holding strange body positions, not talking, resisting instructions, making odd body postures, engaging in restless, purposeless movements, repeating words from others, or performing repetitive actions.

What Are the Signs and Symptoms of Catatonia in Older Adults?

There is a profound lack of psychomotor activity, where the individual appears unresponsive and immobile. The person may maintain rigid or bizarre body positions for extended periods if placed in those positions by others. A marked reduction in verbal responsiveness, where the individual may not speak or respond to verbal cues. Opposition or resistance to attempts to move or instruct the person.

For instance, if someone tries to move their arm, they may resist actively. Assuming unusual or fixed bodily positions, often without any apparent purpose. Intense, purposeless motor activity can be in contrast to periods of immobility. Repetition of words or phrases spoken by others, often without comprehending their meaning. Repetitive, purposeless movements or gestures, such as repeatedly touching one's face or performing the same action repeatedly. Involuntary facial movements or grimacing expressions. Displaying peculiar or idiosyncratic behaviors and mannerisms. Early recognition of catatonia enhances the overall well-being of older adults with catatonia.

What Are the Complications of Catatonia in Older Adults?

1. Malnutrition and Dehydration:

Catatonia can lead to a refusal to eat, resulting in severe malnutrition. Older individuals with catatonia may struggle to maintain proper nutrition due to immobility and decreased food intake, weakening their overall health. Dehydration is a common risk due to reduced fluid intake when individuals with catatonia refuse to drink. It can lead to serious health issues, especially in older adults who are already more susceptible to dehydration-related complications.

2. Deep Vein Thrombosis (DVT):

Prolonged immobility in catatonic older adults increases the risk of DVT, where blood clots form in the deep veins of the legs. If a clot dislodges and reaches the lungs, it can cause a life-threatening pulmonary embolism.

3. Pressure Ulcers (Bedsores):

Because of their prolonged immobility, older individuals with catatonia are at a high risk of developing pressure ulcers, also known as bedsores. These can be painful, difficult to treat, and prone to infection.

4. Muscle Weakness and Atrophy:

Lack of movement and muscle use can lead to muscle weakness and atrophy, further exacerbating mobility issues and making it difficult for individuals to regain their physical functioning.

5. Contractures:

Catatonic older adults may develop contractures, where the muscles and tendons around a joint become permanently shortened, limiting joint movement. This can cause pain and further restrict mobility.

6. Psychological Distress:

Catatonia can be distressing for both the individual and their caregivers. The patient's inability to communicate or engage in self-care can contribute to feelings of frustration, anxiety, and depression.

7. Psychiatric Comorbidities and Delayed Diagnosis:

Catatonia may co-occur with other psychiatric conditions like depression, schizophrenia, or bipolar disorder in older adults, complicating the clinical picture and treatment. Misdiagnosis or delayed recognition of catatonia can result in prolonged suffering for the individual and increased healthcare costs due to the need for extended hospitalization.

It is essential to promptly identify and treat catatonia in older adults to minimize these complications. Healthcare professionals should be vigilant in assessing older individuals for signs of catatonia, especially if they exhibit unusual motor and behavioral symptoms, to ensure appropriate care and prevent these potentially severe complications.

What Kind of Drugs Are Used for Catatonia in Older Adults?

A. Benzodiazepines:

Benzodiazepineslike Lorazepam (Ativan) and Diazepam (Valium) are commonly used to treat catatonia, particularly when there is marked agitation or stupor. First-line treatment results in the relief of symptoms.

B. Electroconvulsive Therapy (ECT):

In severe or treatment-resistant cases of catatonia, especially when there is a risk to the patient's life, Electroconvulsive Therapy (ECT) may be recommended. ECT involves the controlled induction of seizures to alleviate symptoms and is highly effective, even in older adults.

C. NMDA Receptor Antagonists:

Medications like Amantadine and Memantine, which affect NMDA receptors in the brain, have been used in some cases of catatonia, although their efficacy may vary from person to person.

D. Antipsychotic Medications:

Second-generation antipsychotics like Olanzapine may be considered in certain situations, especially if catatonia is associated with psychotic symptoms. However, their use should be cautiously approached in older adults due to potential adverse effects, like stroke.

E. Bromocriptine:

Bromocriptine, a dopamine agonist, has been used in some cases of catatonia, particularly when there is a suspected dopamine imbalance.

F. Benzodiazepine-Sparing Agents:

In cases where long-term treatment is necessary, benzodiazepine-sparing agents like Zolpidem or Zopiclone may be considered to reduce benzodiazepine dependence.

It is important to note that the choice of medication and treatment approach should be tailored to the individual patient's needs and the specific presentation of catatonia. Using these medications in older adults requires careful consideration of their health, potential drug interactions, and any medical condition.

Treatment decisions should be made in consultation with a healthcare professional, typically a psychiatrist or geriatric specialist. Close monitoring and ongoing evaluation are essential for determining the effects of catatonia.

Conclusion

Catatonia can affect older adults, often with serious consequences if left untreated. Recognizing the symptoms, understanding the complications, and selecting appropriate treatment options are crucial in providing effective care to this vulnerable population. Healthcare providers should remain vigilant in assessing older adults, ensuring that catatonia is promptly identified and treated to improve their quality of life and overall well-being.

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Dr. Abhishek Juneja
Dr. Abhishek Juneja

Neurology

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