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Brain Plasticity- Types, Significance, and Neurogenesis

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The article below discusses the commonality between neurogenesis and brain plasticity, both of which are capabilities of the nervous system.

Medically reviewed by

Dr. Abhishek Juneja

Published At June 30, 2023
Reviewed AtJune 30, 2023

Introduction:

The question of whether the brain can change over time has baffled scientists for decades. It is known now that it is possible. This is what neuroscientists call "brain plasticity." It is sometimes associated with a process known as neurogenesis, which is defined as the formation of new neurons. It is also referred to as "neural plasticity" or "neuroplasticity."

Experts agree that the brain's structure and function are far from static, despite the fact that there is still a lot that is yet to be discovered. This article portrays a momentum investigation into brain pliancy and neurogenesis, what they mean for maturing, and how an individual might support their mental well-being.

What Is Brain Plasticity?

The ability of the nervous system to change and reorganize itself throughout a person's life, typically in response to experiences or stimuli, is referred to as "brain plasticity."

Humans, mammals, and vertebrates are not the only animals that undergo this process. Indeed, even insects show brain plasticity, as a matter of fact.

The brain begins to develop in human fetuses a few weeks after conception. While genes serve as the blueprint for brain development, environmental factors like diet, drugs, relationships, stress, and hormones can have a significant impact on the outcome. This is referred to as "developmental brain plasticity," and it continues into childhood.

It is now known that the brain continues to change and adapt well into adulthood. It was once thought that brain development stopped completely a few years after puberty.

Even though the changes are certainly less significant than those that occur in the developing brain, they are essential to our capacity to learn, create memories, and recover from injuries and illnesses.

What Are the Types of Brain Plasticity?

There are two main types of brain plasticity:

  1. Functional Plasticity - The term "functional plasticity" refers to the alteration of neural activity and connectivity in response to particular experiences or events. In order to make up for lost functions, for instance, activity may increase in certain brain regions following an injury like a stroke.

  2. Structural Plasticity - The physical structure of the brain can change as a result of new information and experiences, such as taking music lessons, learning a new language, or exploring the streets of a new city.

How Does Brain Plasticity Work?

Neurons structure the basis of the sensory system. These cells transmit messages throughout the body and are in charge of receiving and processing information from the outside world.

A gap known as a synapse is where neuronal signals, both electrical and chemical, cross. These connections help us learn by forming intricate neural networks.

Having said that, brain plasticity is a complicated process that can change throughout a person's life and involves molecular, cellular, and structural mechanisms.

What Is Neurogenesis?

The development of new neurons is referred to as "neurogenesis." It is a significant piece of brain plasticity, yet by all accounts, it is not the only model.

During the early years of life, when the brain is still developing, the majority of new neurons form. After that, they migrate and differentiate to perform a wide range of nervous system functions. The human brain contains thousands of distinct types of neurons.

As of late, neuroscientists have found proof of grown-up neurogenesis, yet it is as yet a subject of extreme discussion.

A 2019 review suggests that neurogenesis likely takes place in two brain regions:

  1. Long-term memory and learning may be affected by the formation of new neurons in the hippocampus.

  2. The development of new neurons in the subventricular zone has been linked to our sense of smell.

What Is the Significance of Brain Plasticity and Neurogenesis?

From the time an embryo's nervous system begins to form, brain plasticity is essential to human development. As a matter of fact, it is difficult to envision what human existence would resemble in the event that the mind did not change and develop.

Is it possible to continue to be distinctive individuals if there is a lack of the capacity to learn from new stimuli? Would it be possible to improve the abilities, acquire knowledge, or remember things? Would stroke or traumatic brain injury victims be able to recover?

All of these adaptive abilities are influenced by brain plasticity.

The significance of neurogenesis and neuroplasticity in aging is also the subject of a number of current research studies. In particular, animal research shows that hippocampal neurogenesis may protect against cognitive decline and age-related diseases like stroke and Alzheimer's.

How to Boost Brain Plasticity and Neurogenesis?

The capacity for brain plasticity varies greatly from person to person. Researchers believe that personality and lifestyle also play a role, in addition to age.

With certain behaviors, it might be possible to increase neuroplasticity and neurogenesis if that is the case. This includes the demonstrated actions listed below:

1. Regular Exercise: Engaging in regular physical activity encourages neuroplasticity. Finding a worthwhile activity is necessary in order to incorporate exercise into one's life and continue doing so on a regular basis.

2. Management of Stress: A review published in 2022 found that stress can inhibit neurogenesis and neural plasticity. Despite the fact that it is unrealistic to keep away from pressure through and through, an individual can do whatever it takes to limit and deal with its effects.

3. A Healthy Diet: Studies show that diets high in sugar and fat can hurt adult neurogenesis. Then again, consuming polyphenols, like turmeric, can advance brain adaptability.

4. Lifelong Learning: It is well known that learning improves brain function. Try taking a class, picking up a new language, learning to play an instrument, reading books, playing games, or solving puzzles.

5. Good Quality Sleep: A 2017 study found that good sleep is important for synaptic plasticity. It is suggested to make sleep a priority and try to get 7 to 8 hours of sleep each night.

6. Care for the Mind: Research indicates that depression can impede neural plasticity. Conversely, treatments for depression may increase adult neural plasticity.

7. Treatment for Substance Use Disorders: A 2020 review reveals that substance abuse and alcoholism can impair neuroplasticity. If overseeing or halting liquor or medication use is troublesome, help is accessible at this moment.

Conclusion:

Over the course of a person's lifetime, plasticity enables the brain to adapt to new environments, experiences, and situations. It occurs most frequently in infants and embryos, whose brains are still developing, and it decreases with age.Nevertheless, there are numerous adult instances of neuroplasticity. In fact, research indicates that regions of the brain involved in memory and learning can even produce new neurons. Neurogenesis is the name of this process. A lower risk of cognitive decline with aging has also been linked to increased brain plasticity. Regular exercise, eating a well-balanced diet, practicing stress management, and continuing to learn are just a few easy things that can help improve brain plasticity.

Frequently Asked Questions

1.

Why Is Brain Plasticity Important in Childhood?

Brain plasticity allows the brain to rewire itself in response to childhood experiences. It is critical for shaping the brain's structure and function. High plasticity in childhood likely aids in the development of skills and learning.

2.

What Role Does Brain Plasticity Play in Shaping Mindsets?

Brain plasticity plays an important role in shaping mindsets. Mindsets refer to the established attitudes and beliefs that shape one's thought patterns, perceptions, and behaviors related to certain situations or domains. Since brain plasticity entails the ability of the brain's connections to rewire and change in response to experiences, this phenomenon supports changes in thinking over time. Certain experiences, from impactful life events to small daily interactions, trigger neural changes through plasticity mechanisms.

3.

What’s the Significance of Plasticity in Development?

Plasticity allows organisms to produce different phenotypes (physical traits) from the same genotype. This increases the phenotypic variation available for natural selection to act on. Plasticity provides a basis for adaptive traits to become genetically fixed.

4.

What Does the Concept of Brain Plasticity Entail?

The concept of brain plasticity entails:


The brain can reorganize its connections and functions based on experiences.


- It does this by strengthening or weakening synaptic connections between neurons.


- Plasticity allows the brain to learn new things, recover from injuries, and adapt to new situations.


- The brain remains malleable throughout life, though plasticity declines with age.

5.

At Which Age Is Neuroplasticity Most Pronounced?

- Neuroplasticity is highest in childhood, especially in early childhood.


- The brain has a high capacity to rewire neural circuits during infancy and early childhood.


- Plasticity remains high into adolescence as the brain continues to mature and learn.

6.

Is Adult Neurogenesis a Form of Neuroplasticity?

Adult neurogenesis is a structural form of neuroplasticity that involves the creation of new neurons from neural stem cells in the adult brain. It allows the adult brain to physically rewire itself by adding new neuronal connections and circuits.

7.

Can Fasting Enhance Neurogenesis?

Fasting and calorie restriction have been shown to trigger beneficial stress responses in the brain that can boost neurogenesis. Intermittent fasting promotes neural stem cell growth and new connection formation by prompting neurons to switch to ketones over glucose for energy.

8.

What Natural Methods Can Boost Neurogenesis?

Lifestyle factors and activities have been shown to enhance adult neurogenesis. Exercise increases blood flow, growth factors like brain-derived neurotrophic factor, and neural stem cell proliferation in the hippocampus. Learning new skills or cognitive training that enhances mental stimulation can also trigger neurogenesis.

9.

Which Foods Promote the Generation of New Brain Cells?

Dietary components like flavonoids in fruits, tea, dark chocolate(cocoa), and curcumin may stimulate neurogenesis, mostly by reducing inflammation or increasing growth factor signaling. Omega 3 fatty acids, like those in fish and walnuts, support neuron growth and synapse formation. Calorie restriction or fasting triggers neuronal autophagy (a process where nerve cells clean up and recycle their damaged or unnecessary parts to maintain health and function) and regeneration.

10.

Is It Possible for Brain Cells to Regenerate Later in Life?

The brain can regenerate neurons in later life through the process of neurogenesis. The brain maintains a supply of neural stem cells that can differentiate into new neurons to replace damaged ones or form new connections. The regenerative capacity of brain cells persists throughout adulthood, enabling plasticity and some self-repair, although neurogenesis declines with advancing age.

11.

What Type of Exercise Best Stimulates Neurogenesis?

Aerobic exercises like slow running or swimming have been shown to stimulate neurogenesis the most, and this is done by increasing blood flow and oxygen to the brain. These activities can also boost the release of growth factors that support the growth of new brain cells, especially in the hippocampus, the part of the brain associated with learning and memory.

12.

Is Neurogenesis Beneficial for the Brain?

Neurogenesis is highly beneficial for the brain’s health and function. It helps with improved learning, memory, and cognitive flexibility. It also contributes to mood regulation and helps in recovery from trauma, brain injuries, and other neurological conditions.

13.

How Fast Can Brain Rewiring Happen?

Brain rewiring, also called neuroplasticity, can occur at different speeds based on the individual’s age, type of change, and individual differences. It can happen within minutes, or hours, as and when something new is introduced or adapting to a new environment.

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Dr. Abhishek Juneja
Dr. Abhishek Juneja

Neurology

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