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Emergency Treatment of Rabies - A Race Against Time

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A patient with rabies will need to get many vaccinations and injections of immunoglobulin. Read this article to learn more.

Written by

Dr. Kinjal Shah

Medically reviewed by

Dr. Kaushal Bhavsar

Published At November 22, 2023
Reviewed AtNovember 22, 2023

Introduction

When an individual is bitten by a potentially rabid animal, discerning whether the rabies virus has been transmitted is nearly impossible at that moment. Often, bite marks may not even be visible. In such cases, healthcare providers may order a battery of tests aimed at detecting the presence of the rabies virus. Doctors typically recommend immediate treatment to prevent the virus from establishing an infection within the body. Once a rabies infection takes hold, effective treatment becomes exceedingly challenging. While a small number of individuals have survived rabies, it is essential to understand that the disease typically results in a fatal outcome.

Hence, in the event of potential rabies exposure, it becomes imperative to undergo a series of vaccinations to thwart the virus from gaining a foothold in the body. This preemptive approach is crucial, as once the symptoms of rabies manifest, the chances of successful treatment dwindle significantly. While a small number of individuals have survived rabies, it is essential to understand that the disease typically results in a fatal outcome.

What Are Rabies?

As rabies is a zoonotic illness, it may spread from animals to people. Although it is most frequently linked to dogs, it may also be spread by bats, raccoons, skunks, and foxes. The virus enters the brain and spinal cord through the nerves, where it causes inflammation that ultimately results in death.

The disease's unrelenting spread makes rabies treatment urgent. The illness is virtually invariably deadly once signs like fever, headache, and agitation start to manifest. Because of this, it is critical to get medical help right away if there are any suspicions that a person may have been exposed to the virus.

What Are the Signs and Symptoms of Rabies?

Depending on the disease's stage, rabies signs and symptoms might change. In the first phases, rabies patients may encounter:

  • Fever.

  • Headache.

  • Muscle ache.

  • Fatigue.

  • A weakened or unpleasant bite site.

  • Tingling, numbness, or pain at the biting site.

  • Alterations in behavior, such as rage or excessive slobbering.

When the illness worsens, people with rabies may develop:

  • Having trouble swallowing.

  • Excessive slobbering.

  • Paralysis.

  • Seizures.

  • Fear of water (hydrophobia).

  • Fear of fresh air or draughts (aerophobia).

  • Delirium (confusion).

  • Coma.

Here are some more considerations regarding rabies symptoms and signs:

  • Rabies symptoms can resemble those of other illnesses like the flu or meningitis.

  • It may take weeks or even months for rabies symptoms to manifest following exposure.

  • Once rabies symptoms start to manifest, there is no treatment.

What Is the Emergency Treatment for Rabies?

There is a deadline to avoid rabies. It is crucial to get medical help right away if someone is bitten or scratched by a possibly rabid animal. It is crucial to remember that it is currently difficult to determine whether the virus has spread. Cleaning the wound, giving rabies immune globulin (RIG) for severe exposures, and a series of rabies vaccines are all common components of immediate therapy. With this strategy, the virus is to be fought off before it enters the central nervous system.

Post-exposure prophylaxis for rabies (PEP) is divided into two parts:

  • Human Rabies Immunoglobulin (HRIG): HRIG is an antibody type that is administered to aid the body in combating the rabies virus. As soon as possible after exposure, it is injected into the wound.

  • Rabies Vaccine: The goal of rabies vaccination is to aid the body in producing its own antibodies to the rabies virus. It is administered by a series of injections, often four in all. The exposure day is the first shot, and the next three photos are delivered on days 3, 7, and 14.

The more quickly PEP is implemented, the more successful it is. Even if one believes the animal that bit the patient was healthy, one must go to the hospital right away. The primary line of defense against rabies following a probable exposure is post-exposure prophylaxis (PEP). PEP entails a series of rabies shots administered over a period of weeks.

The following are some extra PEP considerations:

  1. PEP is not always required. Depending on the type of animal that bit the patient, the severity of the bite, and the immunization history, the choice of whether or not to provide PEP is decided case by case.

  2. PEP may cause unpleasant side effects, including pain, redness, and swelling when it is injected. Most of the time, these side effects are minor and disappear on their own.

  3. PEP is safe for both youngsters and expectant mothers.

What Are the Complications of Rabies?

The disease is virtually always lethal once the rabies virus has infected the central nervous system and clinical signs start to manifest. Fever, agitation, hallucinations, paralysis, and ultimately coma, and death are some of the signs of rabies. The severe rabies consequences might result in a traumatic and agonizing death.

It is crucial to emphasize that although there have been incredibly few cases of people surviving rabies, they are the exception rather than the norm. The only reliable method to stop the illness from progressing is timely PEP.

How to Prevent Rabies?

Rabies prevention is essential, especially in areas where the virus is prevalent. There are several crucial steps that may be taken to stop the spread of rabies:

  • Pets should be vaccinated against rabies. In particular, make sure that dogs and cats are given this shot.

  • Take action to limit stray and wild animal populations to lower the chance of coming into contact with animals that might be rabid.

  • Spread knowledge about the dangers of rabies and the necessity of receiving prompt medical assistance in the event of an animal bite or scratch.

  • People who are at a high risk of contracting rabies, such as veterinarians and wildlife specialists, should think about getting pre-exposure rabies immunizations.

  • Avoid engaging in activities that might expose oneself to animals that could be rabid, including handling bats or raccoons.

Conclusion

It is critical to seek medical help right away if someone thinks they may have been exposed to the virus. The virus can be stopped from developing into its lethal form by post-exposure prophylaxis, which includes rabies vaccines and, if required, rabies immune globulin. Keep in mind that while rabies is avoidable with timely and adequate medical attention, it is mostly incurable once symptoms show. To save lives and stop the spread of this fatal illness, it is essential to raise awareness and promote education on rabies prevention, especially in areas where the virus is endemic. Education and preventive measures like pet vaccinations are essential weapons in the battle against rabies. Taking prompt action in the face of this deadly viral menace might be the difference between life and death.

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Dr. Kaushal Bhavsar
Dr. Kaushal Bhavsar

Pulmonology (Asthma Doctors)

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