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Neuraxial Anesthesia - Types, Uses, and Side Effects

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Neuraxial anesthesia is administered around the nerve roots present in the spinal cord. Read more to learn about neuraxial anesthesia.

Medically reviewed by

Dr. Kaushal Bhavsar

Published At June 20, 2023
Reviewed AtJune 20, 2023

Introduction:

Anesthesia is used in surgeries to control pain. Anesthesia is of different types and is delivered in different modes to the patient. General, local, and regional anesthesia and sedation are the four types of anesthesia. Under regional anesthesia, many significant surgeries are performed, like cesarean section. Neuraxial anesthesia is a kind of regional anesthesia. This topic explains neuraxial anesthesia, its types, usage, and side effects.

What Is Neuraxial Anesthesia?

Neuraxial anesthesia is a type of regional anesthesia that involves an injection in the surrounding nerve roots present in the spine. It consists of the spine's epidural space and the spinal sac containing cerebrospinal fluid around the spinal cord. Neuraxial anesthesia numbs the area below the injection site covering the lower abdomen and the legs.

What Is Regional Anesthesia?

Regional anesthesia is a type of anesthesia used to numb the more significant body parts. It blocks the nerve signals going to the brain from the targeted surgical site and controls the pain during surgical procedures. Under regional anesthesia, many major surgical procedures can be performed, like cesarean sections and knee surgeries. In addition, the neuraxial is a part of regional anesthesia.

What Are the Types of Neuraxial Anesthesia?

There are four types of most commonly used neuraxial anesthesia. They are as follows:

  1. Spinal Anesthesia - Anesthesia is delivered in the spinal sac, which can block the spine's nerves surrounding the spinal cord. Spinal anesthesia injection is given deep, crossing the skin, subcutaneous fat layer, ligaments, and epidural space and reaching the spinal sac containing cerebrospinal fluid and spinal cord. It is used to numb the lower abdomen as it is given at the lumbar area of the backbone.

  2. Epidural Anesthesia - Anesthesia is delivered in epidural space, where it blocks the nerves exiting the spine. Epidural anesthesia is also given deep but one layer behind spinal anesthesia. It crosses the skin, fat layers, ligaments, and epidural space. Epidural space has nerves that leave the spinal column; anesthesia medicine numbs these nerves and blocks their pain sensations. It is given to numb the lower abdomen and the legs.

  3. Combined Spinal-Epidural Anesthesia - Combined spinal-epidural anesthesia is used as it provides better results than individually administered spinal or epidural anesthesia. The combined form provides rapid onset and more effective results. Instead of using a single injection, it employs a single spinal anesthetic shot, followed by an epidural anesthetic delivered via catheter for use during subsequent procedures or as a postoperative painkiller. It numbs the lower abdomen, lower back, and legs but with more effectiveness.

  4. Caudal Anesthesia - Anesthesia is delivered at the caudal epidural site (the tailbone of the spine). It is delivered in epidural space but in the tailbone (a small bone at the bottom of the spine). It is used to numb the areas of the leg and pelvis.

What Are the Uses of Neuraxial Anesthesia?

The uses of neuraxial anesthesia are:

  • Obstetric Surgery - Obstetrics is a branch that deals in the pregnancy, delivery, and post-delivery period. It includes-

  • Cesarean Surgery - It is done to deliver the baby by incision, not vaginally.

  • Hysterectomy - It is a procedure to remove the womb of a woman.

  • Tubectomy - It is the procedure to block the fallopian tubes for permanent contraception.

  • Cervical Surgery - It is a surgical procedure on the cervix of the woman, the upper part of the vagina.

  • Ovarian Surgeries - It is a surgical procedure to remove one of the ovaries.

  • Tuboplasty - It is the surgical repair of fallopian tubes.

  • Myomectomy - It is a surgical procedure to remove fibroids from the uterus

  • Non-Obstetric Surgery - Non-obstetric surgery is surgery excluding the obstetric branch (delivery or postpartum or pregnancy period). It includes-

  • Orthopedic surgery of lower limbs and pelvis involves hip fracture and knee replacement.

  • General surgery involves appendix, hernia, and testis surgeries.

  • Urological surgeries include bladder, stone in the ureter, and prostate surgery.

  • Surgeries of the upper abdomen.

  • As postsurgical analgesia, the medicine is delivered after the surgery to relieve the pain occurring after the surgery.

  • Caudal anesthesia can be used in children for surgeries on the lower abdomen.

What Are the Side Effects of Neuraxial Anesthesia?

Side effects of neuraxial anesthesia are:

  • Infection.

  • Bleeding.

  • A sudden drop in blood pressure.

  • Severe headache.

  • Nausea.

  • Itchiness on the skin.

  • Dizziness.

  • Allergic reaction.

  • Urinary retention.

  • Fever.

  • Shivering.

  • Breathing problems.

  • Seizures.

  • Spinal cord damage.

  • Nerve injury.

  • Cardiac arrest.

What Are the Anesthetic Agents Used in Neuraxial Anesthesia?

Anesthetic agents that are commonly used in neuraxial anesthesia are:

  • Lidocaine.

  • Bupivacaine.

  • Ropivacaine.

  • Levobupivacaine.

What Are the Contraindications to Neuraxial Anesthesia?

Contraindications to neuraxial anesthesia are:

  • Allergy to anesthetic drugs.

  • Localized infection.

  • Any previous spinal cord injury present, like spinal stenosis (narrowing of the spinal cord).

  • When the patient refuses to go for it.

  • The patient takes anticoagulants, which stop blood clots from forming.

What Is the Difference Between Regional and Neuraxial Anesthesia?

Regional anesthesia is used to numb the large body area, like the entire arm or leg, whereas neuraxial anesthesia is delivered only in the spinal area involving the spine. Neuraxial is a part of regional anesthesia. The neuraxial also numbs the legs and lower abdomen.

Can Neuraxial Be Performed in Child Patients?

Yes, neuraxial anesthesia can be performed in child patients also. Caudal anesthesia is mainly used in child patients for pelvic surgeries. Caudal anesthesia can be used with general anesthesia in child patients.

Is Combined Spinal-Epidural Anesthesia Better Than Individually Used Spinal or Epidural Anesthesia?

Yes, combined spinal-epidurals are better than individual use of spinal or epidurals. Combined spinal-epidural anesthesia is advantageous as it provides rapid onset with better pain suppression. In addition, the amount of medicine (anesthesia) used affects the baby and the patient's body less. Using individual spinal or epidural is not as effective as the combination.

Conclusion:

Neuraxial anesthesia is a kind of regional anesthesia used to inject anesthesia into the spinal area of the spine. It is used to numb the area of the spine. It has four types; epidural, spinal, combined spinal-epidural, and caudal anesthesia. It is commonly used in cesarean sections. Other uses of neuraxial anesthesia include postsurgical analgesia, orthopedic surgery, obstetric surgery, and urological surgeries. Neuraxial anesthesia side effects and contraindications are mentioned in the above topic.

Frequently Asked Questions

1.

What Is Meant by Neuraxial Analgesia?

It is a medical procedure where medications are administered into the subarachnoid or epidural space to produce anesthetic and analgesic effects. As a result, the individual loses complete sensation or motor function below the injection site.

2.

What Is Meant by Neuraxial Nerve Block?

A neuraxial nerve block is a form of regional anesthesia. The procedure includes injecting local anesthetic into the subarachnoid or epidural space of the spinal cord. It inhibits the transmission of pain signals from the nerves in the spinal cord.

3.

What Effect Does Neuraxial Anesthesia Produce?

The anesthesia is administered into the epidural space to block the central nervous system. Neuraxial anesthesia could produce sensory and motor effects. Sensory effects include loss of sensation, whereas motor effects include loss of muscle tone. 

4.

What Risks Are Associated With Neuraxial Anesthesia?

Some risks associated with neuraxial anesthesia are headaches, nerve damage, infection, bleeding, and allergic reactions. The risks can be minimized if the anesthesia is administered by a well-trained anesthesiologist.

5.

Are Neuraxial Anesthesia and Regional Anesthesia the Same?

Neuraxial anesthesia is a type of regional anesthesia. In neuraxial anesthesia, local anesthetics are injected into epidural and subarachnoid space to prevent pain signal transmission from the spinal cord to the brain.

6.

What Are the Differentiating Features of Spinal and Epidural Anesthesia?

The differentiating features are:
- Epidurals take longer to act and last longer, whereas spinal anesthesia works quickly but does not last long.
- Spinal anesthesia is used only for surgical procedures, but epidurals are used for end-of-life care.
- Spinal anesthesia is injected into the subarachnoid space, but epidural anesthesia is administered into the epidural space.

7.

Which Anesthesia Is Preferred for C-Sections?

The best anesthesia for a C-section is selected based on the patient’s medical history, need for anesthesia during labor, or planned C-section. Regional anesthesia, such as spinal and epidural, is preferred. However, spinal anesthesia is more effective than epidural for labor.

8.

What Are the Advantages of Epidural and Spinal Anesthesia?

Epidural and spinal anesthesia are both used in obstetrics procedures. However, both these anesthetic procedures have their advantages, which are:
- Epidural Anesthesia
- It can be used for longer procedures.
- Provides continuous pain relief.
- The doses can be altered based on the requirement.
- Spinal Anesthesia
- Injection provides immediate pain relief.
- The required dose for pain relief is less than the epidural.
- A catheter is not required.

9.

Does Spinal Anesthesia Induce the Same Effect as an Epidural for a C-Section?

Epidural is injected into epidural space, whereas spinal anesthesia is injected into a dural sac containing cerebrospinal fluid. As a result, spinal anesthesia provides faster pain relief than epidural anesthesia. The spinal anesthesia is given as a single shot.

10.

What Are the Side Effects of Neuraxial Anesthesia?

Some of the side effects are:
- Hypotension: Sympathetic blockage caused by anesthesia causes vasodilation and reduced venous return to the heart. As a result, maternal hypertension develops.
- Nausea and Vomiting: It is one of the most common side effects. The symptoms are enhanced when anesthetics containing opioids are used.
- Pruritus: Itching commonly develops when anesthetic-containing opiates are used.

11.

What Is the Common Complication Due to Neuraxial Anesthesia?

Neuraxial anesthesia given for labor or delivery is usually safe. The complications arise due to the physiological or direct effects of local anesthesia. Postdural puncture headache is a common complication due to neuraxial anesthesia.

12.

What Are the Neurological Adverse Effects Due to Neuraxial Anesthesia?

Some neurological side effects are spinal hematoma or central nervous system infections. Neurological effects of neuraxial anesthesia are caused by spinal cord ischemia, traumatic injury to the spinal cord during needle insertion of catheter placement, infection, or type of local anesthetic used. 

13.

What Consequences Are Caused by Spinal Anesthesia Over the Long Term?

Long-term effects of spinal anesthesia are persistent back pain, tingling or numbness in the legs, or muscle weakness. However, the adverse effects caused by spinal anesthesia are rare and can last for weeks or months.

14.

What Is the Highest Complication of Spinal Anesthesia?

The highest complication of spinal anesthesia is total spinal anesthesia. It is caused when injecting local anesthetic affects the spinal nerves above T4. As a result, the patient may develop respiratory or cardiac compromise.

15.

Can Nerve Damage Occur From Spinal Anesthesia?

Spinal anesthesia can induce nerve damage. Patients develop symptoms based on the type of nerve affected or the severity of the damage. The induced nerve damage is mostly temporary and a rare complication of spinal anesthesia. 
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Dr. Kaushal Bhavsar
Dr. Kaushal Bhavsar

Pulmonology (Asthma Doctors)

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