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Link Between Shoulder Pain and Breast Cancer

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Shoulder discomfort is not a common early indication of breast cancer, but it might occasionally occur.

Written byDr. Palak Jain

Medically reviewed byDr. Rajesh Gulati

Published At July 17, 2023
Reviewed AtFebruary 5, 2025

Introduction

Breast cancer does not commonly cause pain. However, shoulder blade pain can occasionally result from breast cancer that has metastasized (spread to other body regions). The bones are one of the most typical sites for breast cancer metastases. Pain may be brought on by the malignancy itself, like a cancerous lump on the shoulder, or by fractures that develop when bones deteriorate. Cancers of the uterus, thyroid, bladder, prostate, lung, and kidney can also metastasize to the bones.

Additionally, the malignancies of the lung and kidney are known to spread to the shoulder joint and shoulder blade. Since part of the nerve networks that surround the liver are descended from the same nerves that attach at the right shoulder blade, discomfort near the right shoulder may also be a sign that breast cancer has spread to the liver. The patient could experience shoulder pain as a result of chemotherapy, radiation therapy, or surgery.

Can Breast Cancer Cause Shoulder Pain?

Although shoulder discomfort is not one of the most typical signs of breast cancer, it might occasionally occur. The following situations can result in shoulder pain:

  • Advanced Breast Cancer: Advanced breast cancer has the potential to metastasize or spread to other body areas, including the bones including the shoulder region. Shoulder or upper back pain may result from this.

  • Referred Pain: Shoulder pain might be caused by a tumor pressing on nerves in the breast or chest wall.

  • Effects of Post-Surgery or Treatment: Following breast cancer therapies, including radiation therapy, lymph node removal, or surgery (mastectomy or lumpectomy), shoulder pain may arise. These therapies may cause discomfort in the form of stiffness, scar tissue, or nerve irritation.

  • Inflammation or lymphedema: Following the excision of lymph nodes, lymphedema (swelling brought on by a buildup of lymph fluid) may result in pain and a decreased range of motion in the shoulder region.

Even though shoulder pain by itself is rarely an indication of breast cancer, it should be assessed by a medical professional, particularly if it continues, gets worse, or is accompanied by other symptoms such as breast lumps, skin changes, or unexplained weight loss. For any underlying illness to be managed, early diagnosis and treatment are essential.

What Does Shoulder Pain From Breast Cancer Feel Like?

Breast cancer-related shoulder pain might vary based on the patient and the disease's origin. However, it is frequently described as:

  • Dull Pain: The pain could be a persistent, dull, deep ache in the upper back, shoulder, or space between the shoulder blade.

  • Referred or Radiating Pain: According to some, the pain travels from the breast region or chest to the shoulder. It could have a burning, tingling, or stabbing feeling, similar to nerve discomfort.

  • Stiffness or Limited Movement: Shoulder stiffness, trouble lifting the arm, or a decreased range of motion may accompany discomfort resulting from post-treatment consequences, such as radiation therapy or surgery.

  • Localized or Widespread Pain: The pain may be felt more widely around the shoulder and upper back, or it may be centered in one particular place.

  • Increasing Pain Over Time: If the pain is brought on by metastatic breast cancer that has spread to the bones, it may progressively get worse, last longer, and feel deeper, particularly at night or when moving.

Can Breast Cancer Treatments Cause Shoulder Pain?

Shoulder pain may result from scar tissue, nerve injury, or muscular tension in the chest and shoulder region following procedures such as mastectomy, lumpectomy, or lymph node excision. Following surgery, limited mobility may also be a factor in shoulder stiffness and pain.

Radiation Treatment: Radiation can cause pain and limited range of motion in the chest and shoulder area by causing inflammation, tightness, or scarring. Persistent pain may be caused by damage to nearby tissues or nerves.

Chemotherapy: Although less frequent, shoulder pain is one of the adverse effects of chemotherapy that can affect muscles or joints.

Lymphedema: Shoulder pain and discomfort may result from swelling of the arm or shoulder brought on by fluid accumulation following lymph node excision.

Hormonal Treatment: Treatments such as aromatase inhibitors can cause stiffness or soreness in the joints, including the shoulders.

What Treatments Can Help With Shoulder Pain?

Shoulder pain with breast cancer is treated differently than shoulder pain associated with an injury or musculoskeletal illness. If a patient has shoulder pain as a result of breast cancer, the healthcare team will most likely perform an imaging test such as an X-ray or magnetic resonance imaging (MRI) to determine the location and type of problem.

Treatment may include one or more of the following therapies:

1. Drugs to Treat Bone Metastasis

These medications can aid in the prevention of bone deterioration and its consequences, such as fractures, hypercalcemia, and spinal cord compression. They are administered once a month via intravenous (IV) therapy or as a subcutaneous (under the skin) injection but may be administered less frequently if it is successful. Bisphosphonate medications, such as Pamidronate, Zoledronic acid, and Denosumab, are used to treat bone metastases.

2. Bone Fracture Surgery:

When a broken bone arises as a result of breast cancer, the fracture is repaired surgically. This is commonly accomplished by placing steel support over the fracture.

3. Radiation Therapy

It is used to prevent further damage post-surgery and to treat fractures caused by bone metastases. It is also used to treat hepatic (liver) metastases, which can cause postponed shoulder pain.

4. Pain Medicine

The pain brought on by breast cancer that has spread to the shoulder is managed by a variety of painkillers. The medical team can choose the most appropriate drugs based on the type and origin of the pain. These medications can be given orally, subcutaneously, recto-rectally, intravenously, or with a patient-operated pump.

5. Systemic Therapies

Cancer cells can be attacked throughout the body with systemic therapy. These therapies consist of chemotherapy, hormone therapy, and anti-HER2 targeted medicines.

Conclusion

Although shoulder pain has been linked to breast cancer, it is not a common indicator of the illness. Shoulder pain may also be caused by other problems. When this happens, shoulder pain is often the result of metastasis. When breast cancer cells spread from the breast to another area of the body, this occurs. Morbidity is often caused by bone metastases. Twenty-nine percent of patients who experienced their initial bone relapse went on to experience one or more of the serious consequences that include spinal cord compression, pathological fracture, hypercalcemia, and bone destruction. Patients with hypercalcemia had a terrible prognosis, with a median survival time of only three months, while protracted remissions of up to 56 months have been reported. Thus, one should be aware of these symptoms to get prompt treatment for a healthy and pain-free life.

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