Relation Between Rick Simpson Oil and Cancer

Introduction

Cancer is the sixth-leading cause of mortality in the world. According to the World health organization (WHO), cancer deaths account for 10 million. An appropriate cancer diagnosis and treatment are crucial for suitable and efficient therapy. Surgery, radiation, and systemic therapies, including chemotherapy, are frequently used in these cancer treatments. Chemotherapy is an effective treatment for many cancer kinds, but it has serious adverse effects on the patient's body. For example, chemotherapy leads to hair loss, weight loss, and more adverse effects on the patient’s body.

Rick Simpson is a scientist who invented Rick Simpson oil, which is claimed for an anti-cancer (antineoplastic) effect. Rick Simpson Oil (RSO) is extracted from cannabis (marijuana), and it is high in tetrahydrocannabinol (THC), which is claimed to treatment for cancer. Several studies consider THC an alternative that can produce the same effects without suffering negative consequences. Since 2009, thousands of patients and their families have received natural cancer treatment from Rick Simpson and his Rick Simpson Oil (RSO).

What Is Rick Simpson Oil?

RSO is a well-known cannabis product many people use to treat cancer and is considered an alternative to chemotherapy and radiation. Rick Simpson Oil (RSO) is extracted from cannabis (marijuana) plant flowers. There are numerous varieties and compositions of cannabis oil. Cannabidiol (CBD) oil, which is frequently included in medical marijuana, is one of these. Rick Simpson Oil is high in tetrahydrocannabinol (THC), the primary psychoactive component of marijuana, compared to many other cannabis oils. The component of marijuana, known as THC, treats cancer. Simpson is an engineer and cannabis activist who introduced Rick Simpson oil and claimed the anti-neoplastic effect on cancerous cells. In addition, he discovered that marijuana reduced his symptoms of disorientation and other after-fall effects.

How Rick Simpson Oil Is Derived?

Rick Simpson Oil (RSO) is a type of cannabis oil that is made using a specific extraction method. The process involves using high-proof alcohol (such as ethanol) to extract the active compounds from the cannabis plant. Here are the general steps for making RSO:

• Start with high-quality, dried cannabis flowers or trim.

• Grind the cannabis material into a fine consistency.

• Place the ground cannabis material into a large container or bucket.

• Add enough high-proof alcohol to cover the cannabis material.

• Mix the cannabis and alcohol together thoroughly using a large spoon or paddle.

• Let the mixture sit for a period of time, usually several hours or overnight, to allow the alcohol to extract the active compounds from the cannabis.

• After the extraction period, strain the mixture through a fine mesh strainer or cheesecloth to remove the plant material.

• The resulting liquid is then heated to remove the alcohol, leaving behind a concentrated cannabis oil.

• The final step is to transfer the oil to a storage container, such as a syringe or small jar, for use.

It's important to note that making RSO can be a potentially dangerous process, as high-proof alcohol is highly flammable and should be used with extreme caution. It's also important to use only high-quality, lab-tested cannabis to ensure the safety and efficacy of the final product.

What Are the Benefits of Rick Simpson Oil?

Rick Simpson Oil (RSO) is rich in Cannabinol (CBN) and tetrahydrocannabinol (THC) which is extracted from cannabis (marijuana). Cannabis has therapeutic use in many diseases.

The following are the uses of cannabis in medicine:

• Cannabis stimulates the appetite and enhances food intake. In addition, it controls appetite and regulates body weight.

• Cannabis has a metabolic effect, and it controls obesity.

• Cannabis treats Mediterranean fever, chronic relapsing pain, and gastrointestinal inflammation.

• THC lessens the side-effect caused by chemotherapy.

• Cannabis compounds are effective in reducing chemo-related illnesses.

• Cannabis has been used for thousands of years to treat pain.

• It is used for mild analgesic effects.

• Cannabis cures muscle pain, inflammation, neurodegenerative diseases, nausea, anxiety, nerve pain, and depression.

• A synthetic cannabinoid called nabilone is authorized to treat severe nausea and vomiting brought on by cancer chemotherapy.

• Ajalemic acid (AJA), another cannabinoid, was successful in relieving persistent neuropathic pain.

Can Rick Simpson Oil Treat Cancer?

• Several studies show antineoplastic (works against cancer) effect against three animal tumor models was examined in four cannabinoids, as well as cytotoxic (killing tumor cells) or cytostatic action in two tumor cell lines and in vitro (in lab) bone marrow cells. The cannabinoids that are effective against Lewis lung tumor cells in vivo are also effective against those same cells in in vitro systems. Since AS-THC and Cannabinol (CBN) are equally active in these systems, it is unusual that Lewis lung cells and bone marrow cells respond differently to A9-THC.

• According to Johnson and Wiersema, AS-THC given intravenously decreases bone marrow cancer cells while increasing lymphocytes (white blood cells). The quick screening and assessment of medication sensitivity are made possible by the use of isolated bone marrow cells during the lab experiment, which represents the antineoplastic effect in rapidly growing tissue.

• The development of tolerance to several of cannabis' behavioral effects is one issue associated with their use. This may be due partly to medication regimens, dosages, and enhanced drug metabolism. Excessive drug usage signifies some alterations to tumor cells that make them resistant to these medications. The high growth fraction and rapid doubling period of this tumor may be the apparent cause of this disparity.

• The potential of THC to block nucleic acid synthesis may contribute to the drug's capacity to reduce tumor growth and increase animal survival after treatment.

• THC potentially has significant physiologic implications due to its antineoplastic action. In humans, the high doses of Ll-9-THC are intolerable. The greatest doses ever given to a human were between 250 and 300 mg. It is irrelevant whether or not only cannabinoids in the central nervous system (CNS) possess this anti-cancer function because CBN, which lacks marijuana's psychoactive effects, is highly active in our bodies.

• Structure-activity studies can be used to design and synthesize more active medicines with little to no or minimal CNS activity. These substances are an interesting class of medications since they easily pass the blood-brain barrier and lack many toxic manifestations of currently utilized cytotoxic agents. Therefore it is used in cancer.

Conclusion

Many of the medicines that are utilized today can lead to addiction and are abused. Cannabis has been used as a medicine for many years, but in the last century, it has been removed from therapeutic settings because to abuse and addiction concerns. Now, cannabis’s components and similar chemicals are being used again in clinical settings. One among them is the Rick Simpson oil which enriched in THC. It has an anti-neoplastic effect and therefore claims to have the potential to manage cancer.